Title
New Onset Depression among Children, Adolescents, and Adults with Hidradenitis Suppurativa.
Publication Date
2020
Journal Title
J Am Acad Dermatol
Abstract
BACKGROUND: Information on risk of depression among among children, adolescents and adults with hidradenitis suppurativa (HS) is limited.
OBJECTIVE: To compare risk of new-onset depression in HS patients with that of controls.
METHODS: Retrospective cohort analysis of 49,280 adult and 3,042 pediatric HS patients and matched controls identified using electronic health records data. Primary outcome was incident depression.
RESULTS: Crude incidence rate (IR) was 4.8 per 100 person-years in adult HS patients compared to 3.0 per 100 person-years in controls. Among pediatric patients, crude IR was 4.2 per 100 person-years in HS patients compared with 2.3 per 100 person-years in controls. In adjusted analysis, adults and pediatric patients with HS had a 10% (HR, 1.10; 95% CI, 1.07-1.13; p
LIMITATIONS: Patients not seeking care in health systems within the database were not captured.
CONCLUSION: Children, adolescents and adults with HS are at an increased risk for developing depression, independent of other common risk factors for depression.
Document Type
Article
Status
Faculty
Facility
School of Medicine
Primary Department
Dermatology
PMID
DOI
10.1016/j.jaad.2020.05.090