Hyponatremia in the cancer patient.

Publication Date

2020

Journal Title

Kidney Int

Abstract

Hyponatremia is a common electrolyte disorder observed in a wide variety of malignancies and is associated with substantial morbidity and mortality. Newer cancer therapies have improved patient outcomes while also contributing to new cases of hyponatremia. Patients should be monitored closely for the development of vasopressin and non-vasopressin mediated hyponatremia. Acute and symptomatic forms of hyponatremia require urgent intervention, and recent findings also support the correction of chronic "asymptomatic" hyponatremia. Optimizing hyponatremia may reduce medical costs, improve cancer survival, and quality of life. In this manuscript, we review the epidemiology, pathophysiology, etiology, diagnosis and treatment of hyponatremia in the cancer patient.

Document Type

Article

Status

Faculty

Facility

School of Medicine

Primary Department

Nephrology

PMID

32497528

DOI

10.1016/j.kint.2020.05.015

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