Publication Date

2015

Journal Title

World J Gastrointest Endosc

Abstract

AIM: To investigate the safety profile of acquiring additional intestinal biopsies for research purposes in children undergoing a medically indicated colonoscopy. METHODS: A retrospective review of 122 pediatric patients who underwent colonoscopy over a 9 mo time period was completed. 38/122 participants consented to a research study in which 4 additional biopsies were obtained, in addition to routine biopsies. The outcomes after colonoscopy were measured in the research participants, and compared to 84 control participants who did not consent for the study. Groups were compared with regard to number of biopsies obtained, underlying diagnosis, and both serious and minor adverse outcomes. Data was collected including: age, gender, race, indication, diagnosis, number of biopsies obtained per case and post procedure adverse events. Medical records were reviewed and a questionnaire was completed by each of the ten gastroenterologists who performed procedures during the study. Physicians were asked about individual patient outcomes to ensure that all adverse events, such as perforation, excessive bleeding, infection, and minor gastrointestinal outcomes, were captured and included. RESULTS: The research group had more biopsies obtained (mean = 13.58 +/- 4.21) compared to controls (mean = 9.33 +/- 4.40), P

Volume Number

7

Issue Number

7

Pages

736-40

Document Type

Article

EPub Date

2015/07/04

Status

Northwell Researcher

Facility

Northwell Health

Primary Department

General Pediatrics

PMID

26140101

DOI

10.4253/wjge.v7.i7.736


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