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Submissions from 2015

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Interactions between Plasmodium falciparum skeleton-binding protein 1 and the membrane skeleton of malaria-infected red blood cells, L. M. Kats, N. I. Proellocks, D. W. Buckingham, L. Blanc, J. Hale, X. Guo, X. Pei, S. Herrmann, E. G. Hanssen, B. M. Cooke, and +3 additional authors

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More data on speed of remission with ECT in geriatric depression, C. H. Kellner, E. T. Geduldig, R. D. Weiner, R. M. Greenberg, J. Prudic, W. V. McCall, G. Petrides, M. M. Husain, M. V. Rudorfer, S. H. Lisanby, and +2 additional authors

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Ribosomopathy association with colorectal cancer, R. Kessel, A. Vlachos, and J. M. Lipton

Bioprinting Complex Cartilaginous Structures with Clinically Compliant Biomaterials, M. Kesti, C. Eberhardt, G. Pagliccia, D. Kenkel, D. Grande, A. Boss, and M. Zenobi-Wong

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ENDOPLASMIC RETICULUM STRESS IN SEPSIS, M. M. Khan, W.L. Yang, and P. Wang

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High-density genotyping of immune loci in Koreans and Europeans identifies eight new rheumatoid arthritis risk loci, K. Kim, S. Y. Bang, H. S. Lee, S. K. Cho, C. B. Choi, Y. K. Sung, T. H. Kim, P. K. Gregersen, S. C. Bae, and +32 additional authors

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Immunological function of Blimp-1 in dendritic cells and relevance to autoimmune diseases, S. J. Kim

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Effects of levodopa on regional cerebral metabolism and blood flow, J. H. Ko, R. P. Lerner, and D. Eidelberg

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Maternal antibodies and developing blood-brain barrier, C. Kowal, A. Athanassiou, H. Chen, and B. Diamond

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Robotics: A Rehabilitation Modality, H. I. Krebs and B. T. Volpe

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Stimulation of Wnt/beta-catenin signaling pathway with Wnt agonist reduces organ injury after hemorrhagic shock, M. Kuncewitch, W.L. Yang, A. Jacob, A. Khader, M. Giangola, Jeffrey Nicastro, G. Coppa, and P. Wang

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[Should antipsychotics be used in prodromal stages of schizophrenia to prevent psychosis? Pro], M. Lambert and C. U. Correll

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Protein domains of APOL1 and its risk variants, X. Q. Lan, H. X. Wen, R. Lederman, A. Malhotra, J. Mikulak, W. Popik, K. Skorecki, and P. C. Singhal

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Apolipoprotein L1 (APOL1) Variants (Vs) a possible link between Heroin-associated Nephropathy (HAN) and HIV-associated Nephropathy (HIVAN), X. Lan, T. K. Rao, P. N. Chander, K. Skorecki, and P. C. Singhal

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Vascular smooth muscle cells contribute to APOL1-induced podocyte injury in HIV milieu, X. Lan, H. Wen, M. A. Saleem, J. Mikulak, A. Malhotra, K. Skorecki, and P. C. Singhal

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The cation channel Trpv2 is a new suppressor of arthritis severity, joint damage, and synovial fibroblast invasion, T. Laragione, K. F. Cheng, M. R. Tanner, M. He, C. Beeton, Y. Al-Abed, and P. S. Gulko

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New data and an old puzzle: the negative association between schizophrenia and rheumatoid arthritis, S. H. Lee, T. Lencz, A. K. Malhotra, H. Medeiros, V. Milanova, J. Shi, P. Sklar, P. K. Gregersen, M. van Laar, P. van Riel, and +134 additional authors

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Widespread non-additive and interaction effects within HLA loci modulate the risk of autoimmune diseases, T. Lencz, A. J. Deutsch, B. Han, X. Hu, Y. Okada, S. Eyre, M. Knapp, A. Zhernakova, P. K. Gregersen, S. Raychaudhuri, and +27 additional authors

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Targeting the schizophrenia genome: a fast track strategy from GWAS to clinic, T. Lencz and A. K. Malhotra

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Services on early recognition of psychoses and bipolar disorders in Germany, K. Leopold, A. Nikolaides, M. Bauer, A. Bechdolf, C. U. Correll, F. Jessen, J. Klosterkotter, S. Ruhrmann, S. Pfeiffer, A. Pfennig, and +3 additional authors

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Analogies for Helping Clinicians and Investigators Better Understand the Principles and Practice of Biostatistics, M. Lesser, M. Akerman, and N. Kohn

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A Case of Phaeohyphomycosis Caused by Exophiala oligosperma in a Renal Transplant Patient Successfully Treated with Posaconazole, A. C. Levy, S Rehman, D.A. Sutton, K.I. Burris, D.A. Hirschwerk, N.P. Wiederhold, J. Lindner, M. Bhaskaran, H.L. Rilo, E.P. Molmenti, and +3 additional authors

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ITI-007 for the Treatment of Schizophrenia: A 4-Week Randomized, Double-Blind, Controlled Trial, J. A. Lieberman, R. E. Davis, C. U. Correll, D. C. Goff, J. M. Kane, C. A. Tamminga, S. Mates, and K. E. Vanover

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DAMP Signaling is a Key Pathway Inducing Immune Modulation after Brain Injury, A. Liesz, A. Dalpke, E. Mracsko, D. J. Antoine, S. Roth, W. Zhou, H. Yang, P. P. Nawroth, K. J. Tracey, R. Veltkamp, and +4 additional authors

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Age influences inflammatory responses, hemodynamics, and cardiac proteasome activation during acute lung injury, H. M. Linge, J. Y. Lee, K. Ochani, K. Koga, N. Kohn, K. Ojamaa, S. R. Powell, and E. J. Miller

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Age-dependent alterations in the inflammatory response to pulmonary challenge, H. M. Linge, K. Ochani, K. Lin, J. Y. Lee, and E. J. Miller

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Curing sickle cell disease: Mission accomplished?, J. M. Lipton

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In memoriam: Robert J. Arceci, J. M. Lipton and P. E. Newburger

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Antipsychotic polypharmacy in schizophrenia patients in China and its association with treatment satisfaction and quality of life: Findings of the third national survey on use of psychotropic medications in China, Q. Li, Y. T. Xiang, Y. A. Su, L. Shu, X. Yu, H. F. Chiu, Christoph Correll, G. S. Ungvari, K. Y. Lai, T. M. Si, and +9 additional authors

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Clozapine in schizophrenia and its association with treatment satisfaction and quality of life: Findings of the three national surveys on use of psychotropic medications in China (2002-2012), Q. Li, Y. T. Xiang, Y. A. Su, L. Shu, X. Yu, C. U. Correll, Q. Y. Mei, K. Q. Li, T. M. Si, J. M. Kane, and +9 additional authors

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Serum Amyloid A Stimulates PKR Expression and HMGB1 Release Possibly through TLR4/RAGE Receptors, W. Li, S. Zhu, J. Li, J. D'Amore, J. D'Angelo, H. Yang, P. Wang, K. J. Tracey, and H. Wang

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Common variants of IRF3 conferring risk of schizophrenia, X. Li, W. Zhang, T. Lencz, A. Darvasi, A. Alkelai, D. F. Zhang, L. Yu, X. F. Xu, M. Li, Y. G. Yao, and +2 additional authors

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Treatment of early non-response in patients with schizophrenia: assessing the efficacy of antipsychotic dose escalation, A. Loebel, L. Citrome, C. U. Correll, J. Xu, J. Cucchiaro, and J. M. Kane

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Recommendations for the monitoring of serum concentrations of antipsychotic drugs in the treatment of schizophrenia, L. V. Lopez and J. M. Kane

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Regulation of post-translational modifications of HMGB1 during immune responses, B. Lu, Y. Tang, X. Zhao, D. Antoine, X. Xiao, H. Wang, U. Andersson, T. Billiar, and K. J. Tracey

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Prognostic role and implications of mutation status of tumor suppressor gene ARID1A in cancer: a systematic review and meta-analysis, C. Luchini, N. Veronese, M. Solmi, H. Cho, J. H. Kim, S. Kyo, S. Y. Lee, D. W. Kim, G. M. Yousef, C. U. Correll, and +22 additional authors

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Immune Dysregulation in Patients Persistently Infected with Human Papillomaviruses 6 and 11, A. V. Lucs, J. A. DeVoti, L. Hatam, A. Afzal, A. L. Abramson, B. M. Steinberg, and V. R. Bonagura

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Introduction to the Special Issue Estradiol and Cognition: Molecules to Mind, V. Luine and M. Frankfurt

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TAT-HSP70 ATTENUATES EXPERIMENTAL LUNG INJURY, M. M. Lyons, N. N. Raj, J. L. Chittams, L. Kilpatrick, and C. S. Deutschman

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Lupus brain fog: a biologic perspective on cognitive impairment, depression, and fatigue in systemic lupus erythematosus, M. Mackay

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Brain metabolism and autoantibody titres predict functional impairment in systemic lupus erythematosus, M. Mackay, C. C. Tang, B. T. Volpe, C. Aranow, P. J. Mattis, R. A. Korff, B. Diamond, and D. Eidelberg

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Joint analysis of psychiatric disorders increases accuracy of risk prediction for schizophrenia, bipolar disorder, and major depressive disorder, R. Maier, G. Moser, C. M. Hultman, M. Landen, D. F. Levinson, K. S. Kendler, J. W. Smoller, N. R. Wray, S. H. Lee, T. Lencz, and +7 additional authors

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Dissecting the Heterogeneity of Treatment Response in First-Episode Schizophrenia, A. K. Malhotra

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Studies on ageing and the severity of radiographic joint damage in rheumatoid arthritis, L. Mangnus, H. W. van Steenbergen, E. Lindqvist, E. Brouwer, M. Reijnierse, T. W. Huizinga, P. K. Gregersen, E. Berglin, S. Rantapaa-Dahlqvist, A. H. van der Helm-van Mil, and +1 additional author

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Functional loss of I kappa B epsilon leads to NF-kappa B deregulation in aggressive chronic lymphocytic leukemia, L. Mansouri, L. A. Sutton, V. Ljungstrom, S. Bondza, L. Arngarden, S. Bhoi, X. J. Yan, N. Chiorazzi, R. Rosenquist, and +25 additional authors

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Weight gain and obesity in schizophrenia: epidemiology, pathobiology, and management, P. Manu, L. Dima, M. Shulman, D. Vancampfort, M. De Hert, and C. U. Correll

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IL-10 restricts dendritic cell (DC) growth at the monocyte-to-monocyte-derived DC interface by disrupting anti-apoptotic and cytoprotective autophagic molecular machinery, C. Martin, M. P. Espaillat, and F. Santiago-Schwarz

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Could the Quick Inventory of Depressive Symptomatology-Self-Report (QIDS-SR) be used in depressed schizophrenia patients?, X. R. Ma, Y. Q. Lin, Y. Li, H. F. K. Chiu, G. S. Ungvari, C. U. Correll, K. Y. C. Lai, M. Y. Cai, J. Yun, Y. T. Xiang, and +5 additional authors

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Reproducibility of a Parkinsonism-Related Metabolic Brain Network in Non-Human Primates: A Descriptive Pilot Study With FDG PET, Y. L. Ma, T. H. Johnston, S. C. Peng, C. T. Zuo, J. B. Koprich, S. H. Fox, Y. H. Guan, D. Eidelberg, and J. M. Brotchie

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Anxiety in youth at clinical high risk for psychosis, L. McAusland, L. Buchy, K. S. Cadenhead, T. D. Cannon, B. A. Cornblatt, E. F. Walker, S. W. Woods, C. E. Bearden, D. H. Mathalon, J. Addington, and +5 additional authors

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A seven-gene expression panel distinguishing clonal expansions of pre-leukemic and chronic lymphocytic leukemia B cells from normal B lymphocytes, B. A. McCarthy, S. Yancopoulos, X. J. Yan, X. P. Wang, W. Li, M. Lesser, S. Paul, E. Boyle, C. Moreno, R. Catera, B. T. Messmer, J. E. Kolitz, S. L. Allen, K. R. Rai, N. Chiorazzi, and +5 additional authors

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Clinical and functional outcomes after 2 years in the early detection and intervention for the prevention of psychosis multisite effectiveness trial, W. R. McFarlane, B. Levin, L. Travis, F. L. Lucas, S. Lynch, M. Verdi, Barbara Cornblatt, S. F. Taylor, A. M. Auther, E. Spring, and +11 additional authors

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Medical Infrared Imaging of Normal and Dysplastic Elbows in Dogs, L. McGowan, C. A. Loughin, D. J. Marino, S. E. Umbaugh, P. Liu, M. Amini, P. Solt, M. Lesser, and M. Akerman

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Abnormal metabolic pattern associated with cognitive impairment in Parkinson's disease: a validation study, S. K. Meles, C. C. Tang, L. K. Teune, R. A. Dierckx, V. Dhawan, P. J. Mattis, K. L. Leenders, and D. Eidelberg

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A Selective Novel Peroxisome Proliferator-Activated Receptor ( PPAR)-alpha Antagonist Induces Apoptosis and Inhibits Proliferation of CLL Cells In Vitro and In Vivo, D. Messmer, K. Lorrain, K. Stebbins, Y. Bravo, N. Stock, G. Cabrera, L. Correa, N. Chiorazzi, X. J. Yan, D. Lorrain, and +4 additional authors

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Genome-wide association study identifies HLA 8.1 ancestral haplotype alleles as major genetic risk factors for myositis phenotypes, F. W. Miller, W. Chen, T. P. O'Hanlon, R. G. Cooper, J. Vencovsky, L. G. Rider, K. Danko, A. Lee, P. K. Gregersen, C. I. Amos, and +17 additional authors

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Predictors of resolution and persistence of renal laboratory abnormalities in pediatric HIV infection, C. D. Mitchell; M. C. Chernoff; G. R., 3rd Seage; M. U. Purswani; H. M. Spiegel; G. Zilleruelo; C. Abitbol; B. Heckman; J. M. Oleske; V. Bonagura; and IMPAACT 219/219C Study Team

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Circulating T cell subsets are altered in individuals with chronic spinal cord injury, R. Monahan, A. Stein, K. Gibbs, M. Bank, and O. Bloom

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TLR-9 and IL-15 Synergy Promotes the In Vitro Clonal Expansion of Chronic Lymphocytic Leukemia B Cells, P. K. A. Mongini, R. Gupta, E. Boyle, J. Nieto, H. Lee, J. Stein, J. Bandovic, T. Stankovic, J. Barrientos, J. E. Kolitz, S. L. Allen, K. Rai, C. C. Chu, and N. Chiorazzi

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The NAVIGATE Program for First-Episode Psychosis: Rationale, Overview, and Description of Psychosocial Components, K. T. Mueser, D. L. Penn, P. Meyer-Kalos, S. R. McGurk, C. Cather, S. Saade, D. G. Robinson, N. R. Schooler, R. A. Rosenheck, J. M. Kane, and +6 additional authors

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Stimulation of Brain AMP-activated Protein Kinase Attenuates Inflammation and Acute Lung Injury in Sepsis, N. Mulchandani, W.L. Yang, M. M. Khan, F. Zhang, P. Marambaud, J. Nicastro, G.F. Coppa, and P. Wang

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Disease-Free Survival According to the Use of Postmastectomy Radiation Therapy After Neoadjuvant Chemotherapy, H. Nagar, D. Boothe, P. S. Ginter, C. Sison, L. Vahdat, S. Shin, M. Smith, K. S. C. Chao, D. Nori, and M. K. Hayes

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Rodent models of neuroinflammation for Alzheimer's disease, A. Nazem, R. Sankowski, M. Bacher, and Y. Al-Abed

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A Stationary Wavelet Entropy-Based Clustering Approach Accurately Predicts Gene Expression, N. Nguyen, A. Vo, I. Choi, and K. J. Won

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Revisiting the Discussion: Termination of Clozapine Treatment Due to Renal Failure Reply, J. Nielsen, P. Manu, J. M. Kane, and C. U. Correll

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Clinical characteristics and influence of childhood trauma on the prodrome of bipolar disorder, M. N. Noto, C. Noto, A. C. Caribe, A. Miranda-Scippa, S. O. Nunes, A. C. Chaves, D. Amino, R. Grassi-Oliveira, C. U. Correll, and E. Brietzke

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Psychiatric genome-wide association study analyses implicate neuronal, immune and histone pathways, C. O'Dushlaine, C. Betancur, S. Herms, R. Krasucki, M. Leboyer, D. H. Ledbetter, T. Lencz, A. K. Malhotra, J. W. Smoller, P. A. Holmans, and +365 additional authors

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Single-Pulse and Unidirectional Electrical Activation of the Cervical Vagus Nerve Reduces Tumor Necrosis Factor in Endotoxemia, P. S. Olofsson, Y.A. Levine, A. Caravaca, S. S. Chavan, V. A. Pavlov, M. Faltys, and K. J. Tracey

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Self-awareness of functional impairment in individuals at clinical high-risk for psychosis, D. M. Olvet, R. E. Carrion, A. M. Auther, and B. A. Cornblatt

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Anti-C1q antibodies in systemic lupus erythematosus, A. M. Orbai, L. Truedsson, G. Sturfelt, O. Nived, H. Fang, G. S. Alarcon, C. Gordon, J. Merrill, C. Aranow, M. Petri, and +43 additional authors

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Objective identification and analysis of physiological and behavioral signs of schizophrenia, M. Osipov, Y. Behzadi, J. M. Kane, G. Petrides, and G. D. Clifford

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PANSS-6: a brief rating scale for the measurement of severity in schizophrenia, S. D. Ostergaard, O. M. Lemming, O. Mors, C. U. Correll, and P. Bech

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Modular Analysis of Peripheral Blood Gene Expression in Rheumatoid Arthritis Captures Reproducible Gene Expression Changes in Tumor Necrosis Factor Responders, M. Oswald, M. E. Curran, S. L. Lamberth, R. M. Townsend, J. D. Hamilton, D. N. Chernoff, M. Kern, C. M. Pond, A. Lee, P. K. Gregersen, and +3 additional authors

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Neutrophil Trafficking in Pulmonary Inflammation: Monitoring Migration and Blockade with 111In-Labeled Leukocytes, C. Palestro, H. M. Linge, K. J. Nichols, K. Ochani, K. Bhargava, and E. J. Miller

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Post splenectomy related pulmonary hypertension, A.V. Palkar, A. Agrawal, S. Verma, A. Iftikhar, E.J. Miller, and A. Talwar

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Impact of early disease factors on metabolic syndrome in systemic lupus erythematosus: data from an international inception cohort, B. Parker, M. B. Urowitz, D. D. Gladman, M. Lunt, R. Donn, S. C. Bae, J. Sanchez-Guerrero, C. Aranow, M. Mackay, I. N. Bruce, and +30 additional authors

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Delayed identification and diagnosis of Huntington's disease due to psychiatric symptoms, A. M. Pascu, P. Ifteni, A. Teodorescu, V. Burtea, and C. U. Correll

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N-Acetylcysteine attenuates tumor necrosis factor alpha levels in autoimmune inner ear disease patients, S. Pathak, C. Stern, and A. Vambutas

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Neural circuitry and immunity, V. Pavlov and K. J. Tracey

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Severity of thought disorder predicts psychosis in persons at clinical high-risk, D. O. Perkins, C. D. Jeffries, B. A. Cornblatt, S. W. Woods, J. Addington, D. H. Mathalon, L. J. Seidman, M. T. Tsuang, E. F. Walker, T. H. McGlashan, and +4 additional authors

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Unmet needs in paediatric psychopharmacology: Present scenario and future perspectives, A. M. Persico, C. Arango, J. K. Buitelaar, C. U. Correll, J. C. Glennon, P. J. Hoekstra, C. Moreno, B. Vitiello, J. Vorstman, and A. Zuddas

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Electroconvulsive therapy augmentation in clozapine-resistant schizophrenia: a prospective, randomized study, G. Petrides, C. Malur, R. J. Braga, S. H. Bailine, N. R. Schooler, A. K. Malhotra, J. M. Kane, S. Sanghani, T. E. Goldberg, M. John, and A. Mendelowitz

Establishing a translational genomics infrastructure in pediatric cancer: the GREAT KIDS experience, N. Pinto, S. L. Volchenboum, A. D. Skol, L. Rhodes, A. Doan, C. Fein-Levy, J. M. Lipton, J. M. Cunningham, and K. Onel

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Rewiring of sIgM-Mediated Intracellular Signaling through the CD180 Toll-like Receptor, N. Porakishvili, K. Vispute, A. J. Steele, N. Rajakaruna, N. Kulikova, T. Tsertsvadze, R. N. Damle, K. R. Rai, N. Chiorazzi, P. M. Lydyard, and +2 additional authors

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Age and sex effects on corpus callosum morphology across the lifespan, D. M. Prendergast, B. Ardekani, T. Ikuta, M. John, B. Peters, P. DeRosse, R. Wellington, A. K. Malhotra, and P. Szeszko

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The HIV protease inhibitor saquinavir inhibits HMGB1 driven inflammation by targeting the interaction of cathepsin V with TLR4/MyD88, J. P. Pribis, Y. Al-Abed, H. Yang, D. Gero, H. Xu, M. F. Montenegro, E. M. Bauer, S. Kim, K. J. Tracey, T. R. Billiar, and +5 additional authors

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Adenocarcinoma arising at ileostomy sites: Two cases and a review of the literature, L. Procaccino, S. Rehman, A. Abdurakhmanov, P. McWhorter, N. La Gamma, M. C. Bhaskaran, J. Maurer, G. M. Grimaldi, H. Rilo, J. Nicastro, G. Coppa, E. P. Molmenti, and J. Procaccino

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Therapeutic potential of new B cell-targeted agents in the treatment of elderly and unfit patients with chronic lymphocytic leukemia, K. R. Rai

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Poly(I:C) induces controlled release of IL-36gamma from keratinocytes in the absence of cell death, A. A. Rana, A. V. Lucs, J. DeVoti, L. Blanc, J. Papoin, R. Wu, C. J. Papayannakos, A. Abramson, V. R. Bonagura, and B. M. Steinberg

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Early stages of bipolar disorder: characterization and strategies for early intervention, A. C. Rios; M. N. Noto; L. B. Rizzo; R. Mansur; F. E., Jr. Martins; R. Grassi-Oliveira; C. U. Correll; and E. Brietzke

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Sudden Cardiac Death in Young Adults With Previous Hospital-Based Psychiatric Inpatient and Outpatient Treatment: A Nationwide Cohort Study From Denmark, B. Risgaard, K. Waagstein, R. Jabbari, T. H. Lynge, C. Glinge, C. Albert, C. U. Correll, S. Haunso, A. Fink-Jensen, J. Tfelt-Hansen, and +1 additional author

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A Randomized Comparison of Aripiprazole and Risperidone for the Acute Treatment of First-Episode Schizophrenia and Related Disorders: 3-Month Outcomes, D. G. Robinson, J. A. Gallego, M. John, G. Petrides, Y. Hassoun, J. P. Zhang, L. Lopez, R. J. Braga, M. Naraine, N. Bennett, J. Greenberg, T. Lencz, C. U. Correll, J. M. Kane, A. K. Malhotra, and +4 additional authors

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Prescription Practices in the Treatment of First-Episode Schizophrenia Spectrum Disorders: Data From the National RAISE-ETP Study, D. G. Robinson, N. R. Schooler, M. John, C. U. Correll, P. Marcy, J. Severe, A. Goldstein, S. Azrin, R. Heinssen, J. M. Kane, and +7 additional authors

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Response to Saraga, Evidence-Based Medicine and Clinical Expertise Response, D. G. Robinson, N. R. Schooler, and J. M. Kane

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Child and Adolescent Psychiatrists' Reported Monitoring Behaviors for Second-Generation Antipsychotics, A. M. Rodday, S. K. Parsons, C. Mankiw, C. U. Correll, A. S. Robb, B. T. Zima, T. S. Saunders, and L. K. Leslie

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Maintenance Electroconvulsive Therapy: Cost-effectiveness and Patient/Family Satisfaction, R. Rodriguez-Jimenez, A. Bagney, I. Torio, M. Caballero, P. Ruiz, F. P. Rivas-Clemente, M. A. Jimenez-Arriero, and G. Petrides

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Xanomeline suppresses excessive pro-inflammatory cytokine responses through neural signal-mediated pathways and improves survival in lethal inflammation, M. Rosas-Ballina, S. I. Valdes-Ferrer, M. E. Dancho, M. Ochani, D. Katz, K. F. Cheng, P. S. Olofsson, S. S. Chavan, Y. Al-Abed, K. J. Tracey, and V. A. Pavlov

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B-1 Cell Development and Function, T. L. Rothstein, L. A. Herzenberg, N. E. Holodick, and E. Ghosn

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The human counterpart of mouse B-1 cells, T. L. Rothstein and T. D. Quach

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The Relationship of Common Risk Variants and Polygenic Risk for Schizophrenia to Sensorimotor Gating, P. Roussos, S. G. Giakoumaki, C. Zouraraki, J. F. Fullard, V. E. Karagiorga, E. M. Tsapakis, Z. Petraki, L. J. Siever, T. Lencz, A. Malhotra, and +2 additional authors