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Submissions from 2015

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The Relationship of Common Risk Variants and Polygenic Risk for Schizophrenia to Sensorimotor Gating, P. Roussos, S. G. Giakoumaki, C. Zouraraki, J. F. Fullard, V. E. Karagiorga, E. M. Tsapakis, Z. Petraki, L. J. Siever, T. Lencz, A. Malhotra, and +2 additional authors

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Molecular Medicine Commemorates the Achievements of the First 20 Years, M. Ruggieri

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Early Improvement As a Predictor of Later Response to Antipsychotics in Schizophrenia: A Diagnostic Test Review, M. T. Samara, Y. C. Chung, B. Crespo-Facorro, H. Elkis, M. M. Leeflang, K. Hatta, I. Giegling, J. M. Kane, C. U. Correll, S. Leucht, and +11 additional authors

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A variable number of tandem repeats in the 3 '-untranslated region of the dopamine transporter modulates striatal function during working memory updating across the adult age span, F. Sambataro, J. E. Podell, V. P. Murty, S. Das, B. Kolachana, T. E. Goldberg, D. R. Weinberger, and V. S. Mattay

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Antipsychotic Treatment and Functional Connectivity of the Striatum in First-Episode Schizophrenia, D. K. Sarpal, D. G. Robinson, T. Lencz, M. Argyelan, T. Ikuta, K. Karlsgodt, J. Gallego, J. M. Kane, P. R. Szeszko, and A. K. Malhotra

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A Common Polymorphism in SCN2A Predicts General Cognitive Ability through Effects on PFC Physiology, M. A. Scult, J. W. Trampush, F. Zheng, E. D. Conley, T. Lencz, A. K. Malhotra, D. Dickinson, D. R. Weinberger, and A. R. Hariri

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Hypothesis: neuroendocrine mechanisms (hypothalamus-growth hormone-STAT5 axis) contribute to sex bias in pulmonary hypertension, P. B. Sehgal, Y. M. Yang, and E. J. Miller

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STAT5a/b contribute to sex bias in vascular disease: A neuroendocrine perspective, P.B. Sehgal, Y. Yang, H. Yuan, and E.J. Miller

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Genome-wide Association Study of Late-Onset Myasthenia Gravis: Confirmation of TNFRSF11A, and Identification of ZBTB10 and Three Distinct HLA Associations, M. F. Seldin, O. K. Alkhairy, A. T. Lee, J. A. Lamb, J. Sussman, R. Pirskanen-Matell, F. Piehl, J. J. Verschuuren, P. K. Gregersen, L. Hammarstrom, and +9 additional authors

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Neural systems mediating decision-making and response inhibition for social and nonsocial stimuli in autism, K. M. Shafritz, J. D. Bregman, T. Ikuta, and P. R. Szeszko

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Judging quality of current septic shock definitions and criteria, M. Shankar-Hari, G. Bertolini, F. M. Brunkhorst, R. Bellomo, D. Annane, C. S. Deutschman, and M. Singer

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Do we need a new definition of sepsis?, M. Shankar-Hari, C. S. Deutschman, and M. Singer

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Biologics in Achilles tendon healing and repair: a review, E. Shapiro, D. Grande, and M. Drakos

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Identification and characterization of distinct IL-17F expression patterns and signaling pathways in chronic lymphocytic leukemia and normal B lymphocytes, B. Sherry, P. Jain, P. Y. Chiu, L. Leung, S. L. Allen, J. E. Kolitz, K. R. Rai, J. Barrientos, S. Liang, R. Hawtin, and N. Chiorazzi

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Patterns of clozapine and other antipsychotics prescriptions in patients with treatment-resistant schizophrenia in community mental health centers in Sao Paulo, Brazil, A. S. D. Silveira, D.M.L.V. Rocha, C. R. D. Attux, C. S. Daltio, L. A. da Silva, H. Elkis, J. M. Kane, and R. A. Bressan

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Pioglitazone in early Parkinson's disease: a phase 2, multicentre, double-blind, randomised trial, T. Simuni, K. Kieburtz, B. Tilley, J. J. Elm, B. Ravina, D. Babcock, M. Emborg, Andrew Feigin, R. Zweig, Parkinson Ninds Exploratory Trials, and +38 additinal authoris

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Clinical and genomic heterogeneity of Diamond Blackfan anemia in the Russian Federation, N. S. Smetanina, I. V. Mersiyanova, M. A. Kurnikova, G. S. Ovsyannikova, L. A. Hachatryan, V. O. Bobrynina, M. A. Maschan, G. A. Novichkova, J. M. Lipton, and A. A. Maschan

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The current state of scaffolds for musculoskeletal regenerative applications, B. D. Smith and D. A. Grande

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Immunology and cartilage regeneration, B. Smith, I. R. Sigal, and D. A. Grande

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Frequency and correlates of antipsychotic polypharmacy among patients with schizophrenia in Denmark: A nation-wide pharmacoepidemiological study, B. Sneider, S. G. Pristed, C. U. Correll, and J. Nielsen

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Inflammatory cytokines and anorexia nervosa: A meta-analysis of cross-sectional and longitudinal studies, M. Solmi, N. Veronese, A. Favaro, P. Santonastaso, E. Manzato, G. Sergi, and C. U. Correll

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Oxidative stress and antioxidant levels in patients with anorexia nervosa: A systematic review and exploratory meta-analysis, M. Solmi, N. Veronese, E. Manzato, G. Sergi, A. Favaro, P. Santonastaso, and C. U. Correll

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Impairments in Negative Facial Emotion Recognition in Chinese Schizophrenia Patients Detected With a Newly Designed Task, Y. Song, Y. T. Xiang, X. Wang, F. Zhang, J. S. Kwan, O. C. Chan, Z. Wang, G. S. Ungvari, C. U. Correll, C. Zaroff, and +2 additional authors

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Lack of cardinal symptoms of meningitis in a hospitalized patient with chronic schizophrenia: lessons to be learned, R. So, T. Hirota, Y. Yamamoto, A. Hishimoto, and C. U. Correll

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Neural and behavioral substrates of disorientation in mild cognitive impairment and Alzheimer's disease, A. Sousa, J. J. Gomar, and T. E. Goldberg

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Macrophage Migration Inhibitory Factor as a Potential Predictor for Requirement of Renal Replacement Therapy After Orthotopic Liver Transplantation, J. Stefaniak, J. Schiefer, E. J. Miller, C. G. Krenn, D. M. Baron, and P. Faybik

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Early response or nonresponse at week 2 and week 3 predict ultimate response or nonresponse in adolescents with schizophrenia treated with olanzapine: results from a 6-week randomized, placebo-controlled trial, M. Stentebjerg-Olesen, S. J. Ganocy, R. L. Findling, K. Chang, M. P. DelBello, J. M. Kane, M. Tohen, P. Jeppesen, and C. U. Correll

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Genome-wide Association Analysis of Psoriatic Arthritis and Cutaneous Psoriasis Reveals Differences in Their Genetic Architecture, P. E. Stuart, R. P. Nair, L. C. Tsoi, T. Tejasvi, S. Das, H. M. Kang, E. Ellinghaus, V. Chandran, K. Callis-Duffin, R. Ike, Y. Li, X. Wen, C. Enerback, J. E. Gudjonsson, S. Koks, K. Kingo, J. Winkelmann, P. K. Gregersen, J. T. Elder, and +30 additional authors

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The prevalence of pain in bipolar disorder: a systematic review and large-scale meta-analysis, B. Stubbs, L. Eggermont, A. J. Mitchell, M. De Hert, C. U. Correll, A. Soundy, S. Rosenbaum, and D. Vancampfort

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Decreased Pain Sensitivity Among People with Schizophrenia: A Meta-analysis of Experimental Pain Induction Studies, B. Stubbs, T. Thompson, S. Acaster, D. Vancampfort, F. Gaughran, and C. U. Correll

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Combination of agomelatine and bupropion for treatment-resistant depression: results from a chart review study including a matched control group, K. W. Suhs, C. U. Correll, C. K. Eberlein, R. Pul, H. Frieling, S. Bleich, and K. G. Kahl

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A proteinuria cut-off level of 0.7 g/day after 12 months of treatment best predicts long-term renal outcome in lupus nephritis: data from the MAINTAIN Nephritis Trial, F. Tamirou, B. R. Lauwerys, M. Dall'Era, M. Mackay, B. Rovin, R. Cervera, F. A. Houssiau, D. Abramowicz, L. de Bruxelles, R. Westhovens, and +35 additional authors

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In Support of a Patient-Driven Initiative and Petition to Lower the High Price of Cancer Drugs, A. Tefferi, K. Rai, A. I. Schafer, C. Schiffer, M. A. Sekeres, L. L. Siu, F. M. Stewart, M. Thompson, J. M. Vose, P. H. Wiernik, and +109 additional authors

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Stroke subtype and motor impairment influence contralesional excitability, G. W. Thickbroom, M. Cortes, A. Rykman, B. T. Volpe, F. Fregni, H. I. Krebs, A. Pascual-Leone, and D. J. Edwards

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Targeting Mutant BRAF in Relapsed or Refractory Hairy-Cell Leukemia, E. Tiacci, J. H. Park, L. De Carolis, S. S. Chung, A. Broccoli, S. Scott, F. Zaja, S. Devlin, K. R. Rai, M. S. Tallman, and +31 additional authors

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Approaching the Next Revolution? Evolutionary Integration of Neural and Immune Pathogen Sensing and Response, K. J. Tracey

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SHOCK MEDICINE, K. J. Tracey

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Exosomes in Cancer Research, S. R. Vaiselbuh

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Risk of metabolic syndrome and its components in people with schizophrenia and related psychotic disorders, bipolar disorder and major depressive disorder: a systematic review and meta-analysis, D. Vancampfort, B. Stubbs, A. J. Mitchell, M. De Hert, M. Wampers, P. B. Ward, S. Rosenbaum, and C. U. Correll

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Association of Valine and Leucine at HLA-DRB1 Position 11 With Radiographic Progression in Rheumatoid Arthritis, Independent of the Shared Epitope Alleles but Not Independent of Anti-Citrullinated Protein Antibodies, H. W. van Steenbergen, S. Raychaudhuri, L. Rodriguez-Rodriguez, S. Rantapaa-Dahlqvist, E. Berglin, R. E. M. Toes, T. W. J. Huizinga, B. Fernandez-Gutierrez, P. K. Gregersen, and A. H. M. van der Helm-van Mil

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A genetic study on C5-TRAF1 and progression of joint damage in rheumatoid arthritis, H. W. van Steenbergen, L. Rodriguez-Rodriguez, E. Berglin, A. Zhernakova, R. Knevel, J. Ivorra-Cortes, T. W. J. Huizinga, B. Fernandez-Gutierrez, P. K. Gregersen, A. H. M. van der Helm-van Mil, and +1 additional author

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Remission in SLE: closing in on the target, R. F. van Vollenhoven, A. Voskuyl, E. Morand, and C. Aranow

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Vitamin K antagonists' use and fracture risk: results from a systematic review and meta-analysis, N. Veronese, G. Bano, G. Bertozzo, S. Granziera, M. Solmi, E. Manzato, G. Sergi, A. T. Cohen, and C. U. Correll

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Inverse relationship between body mass index and mortality in older nursing home residents: a meta-analysis of 19,538 elderly subjects, N. Veronese, E. Manzato, S. Maggi, P. Manu, G. Zuliani, M. Wong, K. Lok, J. Kane, G. Sergi, C. U. Correll, and +29 additional authors

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Modeling Linkage Disequilibrium Increases Accuracy of Polygenic Risk Scores, B. J. Vilhjalmsson, J. Yang, H. K. Finucane, A. Gusev, S. Lindstrom, S. Ripke, R. Tamimi, E. Stahl, A. L. Price, T. Lencz, and +25 additional authors

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Limited Evidence for Association of Genome-Wide Schizophrenia Risk Variants on Cortical Neuroimaging Phenotypes, A. N. Voineskos, D. Felsky, A. L. Wheeler, D. J. Rotenberg, M. Levesque, S. Patel, P. R. Szeszko, J. L. Kennedy, T. Lencz, and A. K. Malhotra

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The brain at risk: the sepsis syndrome and lessons from preclinical experiments, B. T. Volpe, R. A. Berlin, and M. Frankfurt

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Demographic correlates of attenuated positive psychotic symptoms, R. N. Waford, A. MacDonald, K. S. Cadenhead, T. D. Cannon, B. A. Cornblatt, R. Heinssen, D. O. Perkins, L. J. Seidman, S. W. Woods, T. H. McGlashan, and +8 additional authors

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Specificity of Incident Diagnostic Outcomes in Patients at Clinical High Risk for Psychosis, J. R. Webb, J. Addington, D. O. Perkins, C. E. Bearden, K. S. Cadenhead, T. D. Cannon, B. A. Cornblatt, E. F. Walker, T. H. McGlashan, S. W. Woods, and +4 additional authors

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Stress Induces the Danger-Associated Molecular Pattern HMGB-1 in the Hippocampus of Male Sprague Dawley Rats: A Priming Stimulus of Microglia and the NLRP3 Inflammasome, M. D. Weber, M. G. Frank, K. J. Tracey, L. R. Watkins, and S. F. Maier

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Mitochondrial dysfunction in peripheral blood mononuclear cells in pediatric septic shock, S. L. Weiss, M. A. Selak, F. Tuluc, J. Perales Villarroel, V. M. Nadkarni, C. S. Deutschman, and L. B. Becker

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Crossing the Atlantic: The Euro-Lupus Nephritis Regimen in North America, D. Wofsy, B. Diamond, and F. A. Houssiau

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QTc prolongation in schizophrenia patients in Asia: clinical correlates and trends between 2004 and 2008/2009, Y. T. Xiang, H. F. K. Chiu, G. S. Ungvari, C. U. Correll, K. Y. C. Lai, P. Udomratn, K. Y. Chee, N. Sartorius, C. H. Tan, N. Shinfuku, and +12 additional authors

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Use of electroconvulsive therapy for Asian patients with schizophrenia (2001-2009): Trends and correlates, Y. T. Xiang, G. S. Ungvari, C. U. Correll, H. F. Chiu, K. Y. Lai, K. Sim, M. K. Yong, N. Sartorius, C. H. Tan, N. Shinfuku, and +12 additional authors

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Quality of Life in Older Patients With Chronic Obstructive Pulmonary Disease (COPD) in Hong Kong: A Case-Control Study, Y. T. Xiang, T. S. Wong, J. Tsoh, G. S. Ungvari, C. U. Correll, J. Sareen, K. Penner-Goeke, F. W. S. Ko, D. S. C. Hui, and H. F. K. Chiu

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Immunoglobulin heavy variable (IGHV) genes and alleles: new entities, new names and implications for research and prognostication in chronic lymphocytic leukaemia, A. Xochelli, A. Agathangelidis, I. Kavakiotis, E. Minga, L. Sutton, P. Baliakas, L. Bonello, N. Chiorazzi, K. Stamatopoulos, and +18 additional authors

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Temperament and prodromal symptoms prior to first manic/hypomanic episodes: results from a pilot study, E. Zeschel, T. Bingmann, A. Bechdolf, S. Kruger-Oezguerdal, C. U. Correll, K. Leopold, A. Pfennig, M. Bauer, and G. Juckel

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A functional polymorphism in the interleukin-1beta and severity of nicotine dependence in male schizophrenia: a case-control study, X. Y. Zhang, D. C. Chen, Y. L. Tan, S. P. Tan, X. Luo, L. Zuo, W. Rao, Q. Yu, C. Kou, M. Allen, Christoph Correll, J. Wu, and J. C. Soares

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Frequency and Correlates of Distant Visual Impairment in Patients with Schizophrenia, Bipolar Disorder, and Major Depressive Disorder, W. Zheng, L. R. Tang, Christoph Correll, G. S. Ungvari, H. F. Chiu, Y. Q. Xiang, and Y. T. Xiang

Glutamatergic agents for schizophrenia: current evidence and perspectives, M. Zink and Christoph Correll

Submissions from 2014

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Substance use in clinical high risk for psychosis: a review of the literature, J. Addington, N. Case, M. M. Saleem, A. M. Auther, B. A. Cornblatt, and K. S. Cadenhead

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The functions of HMGB1 depend on molecular localization and post-translational modifications Introduction, U. Andersson, D. J. Antoine, and K. J. Tracey

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Prevalence of Nurses' Smoking Habits in Psychiatric and General Hospitals in China, F. R. An, D. S. F. Yu, K. Y. C. Lai, Y. K. Qi, J. Y. Zeng, P. P. Wu, Z. J. Hou, C. U. Correll, R. Newhouse, H. F. K. Chiu, and +5 additional authors

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Choosing Wisely in Critical Care Maximizing Value in the ICU, D. C. Angus, C. S. Deutschman, J. B. Hall, K. C. Wilson, C. L. Munro, and N. S. Hill

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A Systematic Nomenclature for the Redox States of High Mobility Group Box (HMGB) Proteins, D. J. Antoine, H. E. Harris, U. Andersson, K. J. Tracey, and M. E. Bianchi

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Second-Generation Antipsychotic Use in Children and Adolescents: A Six-Month Prospective Cohort Study in Drug-Naive Patients, C. Arango, M. Giraldez, J. Merchan-Naranjo, C. Moreno, P. de Andres, C. Cuerda, E. de la Serna, C. U. Correll, D. Fraguas, M. Parellada, and +4 additional authors

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Treatment of lupus nephritis with abatacept: the Abatacept and Cyclophosphamide Combination Efficacy and Safety Study, A. Askanase, M. Byron, L. Keyes-Elstein, P. Cagnoli, J. McCune, B. Diamond, D. Daikh, A. Davidson, M. Mackay, D. Wofsy, and +24 additional authors

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Treatment of Lupus Nephritis With Abatacept, A. D. Askanase, M. Byron, L. L. Keyes-Elstein, P. C. Cagnoli, W. J. McCune, W. W. Chatham, A. Davidson, B. Diamond, M. Mackay, R. Winchester, and +24 additional authors

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A new system for naming ribosomal proteins, N. Ban, R. Beckmann, J. H. D. Cate, J. D. Dinman, F. Dragon, S. R. Ellis, D. L. J. Lafontaine, L. Lindahl, J. M. Lipton, M. Yusupov, and +15 additional authors

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Lymphoma risk in systemic lupus: effects of disease activity versus treatment, S. Bernatsky, R. Ramsey-Goldman, L. Joseph, J. F. Boivin, K. H. Costenbader, M. B. Urowitz, D. D. Gladman, P. R. Fortin, C. Aranow, A. E. Clarke, and +27 additional authors

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Non-mammalian model systems for studying neuro-immune interactions after spinal cord injury, O. Bloom

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Dose and outcomes in primary immunodeficiency disorders, V. R. Bonagura

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The gut microbiota influences blood-brain barrier permeability in mice, V. Braniste, M. Al-Asmakh, C. Kowal, F. Anuar, A. Abbaspour, M. Toth, A. Korecka, B. T. Volpe, B. Diamond, S. Pettersson, and +8 additional authors

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Factors associated with damage accrual in patients with systemic lupus erythematosus: results from the Systemic Lupus International Collaborating Clinics (SLICC) Inception Cohort, I. N. Bruce, A. G. O'Keeffe, V. Farewell, J. G. Hanly, S. Manzi, L. Su, D. D. Gladman, S. C. Bae, C. Aranow, M. B. Urowitz, and +30 additional authors

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Empirical evidence for discrete neurocognitive subgroups in bipolar disorder: clinical implications, K. E. Burdick, M. Russo, S. Frangou, K. Mahon, R. J. Braga, M. Shanahan, and A. K. Malhotra

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Farewell Statement from Dr. Cerami and Dr. Tracey as Outgoing Co-Editors in Chief of Molecular Medicine, A. Cerami and K. J. Tracey

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Nanocomposite Scaffold for Chondrocyte Growth and Cartilage Tissue Engineering: Effects of Carbon Nanotube Surface Functionalization, N. O. Chahine, N. M. Collette, C. B. Thomas, D. C. Genetos, and G. G. Loots

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Regulating innate immunity with dopamine and electroacupuncture, S. S. Chavan and K. J. Tracey

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Effectiveness of lurasidone in schizophrenia or schizoaffective patients switched from other antipsychotics: a 6-month, open-label, extension study, L. Citrome, P. J. Weiden, J. P. McEvoy, C. U. Correll, J. Cucchiaro, J. Hsu, and A. Loebel

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Validation of ZAP-70 methylation and its relative significance in predicting outcome in chronic lymphocytic leukemia, R. Claus, D. M. Lucas, A. S. Ruppert, K. E. Williams, D. Weng, K. Patterson, M. Zucknick, J. C. Barrientos, K. R. Rai, J. C. Byrd, and +13 additional authors

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Can an early weight management program (WMP) prevent olanzapine (OLZ)-induced disturbances in body weight, blood glucose and lipid metabolism? Twenty-four- and 48-week results from a 6-month randomized trial, J. Cordes, J. Thunker, G. Regenbrecht, J. Zielasek, C. U. Correll, C. Schmidt-Kraepelin, C. Lange-Asschenfeldt, W. Gaebel, A. Klimke, H. Hauner, and +2 additional authors

Recognition of patients who would benefit from LAI antipsychotic treatment: how to assess adherence, C. Correll

Mechanism of action of antipsychotic medications, C. U. Correll

The role of the extended health care team in successful LAI therapy: education to overcome barriers, C. U. Correll

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Efficacy of Pharmacologic and Psychotherapeutic Interventions in Psychiatry To Talk or to Prescribe: Is That the Question?, C. U. Correll and M. Carbon

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Schizophrenia: Mechanism of Action of Current and Novel Treatments, C. U. Correll and J. M. Kane

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Prioritization of Research Addressing Antipsychotics for Adolescents and Young Adults With Bipolar Disorder, M. J. Crowley, D. C. McCrory, R. Chatterjee, J. M. Gierisch, E. R. Myers, K. M. Schmit, R. R. Coeytaux, C. U. Correll, A. S. Kendrick, and G. D. Sanders

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The influence of polygenic risk scores on heritability of anti-CCP level in RA, J. Cui, K. E. Taylor, Y. C. Lee, H. Kallberg, M. E. Weinblatt, J. S. Coblyn, L. Klareskog, L. A. Criswell, P. K. Gregersen, E. W. Karlson, and +2 additional authors

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Interferon alpha on NZM2328.Lc1R27: Enhancing autoimmunity and immune complex-mediated glomerulonephritis without end stage renal failure, C. Dai, H. Y. Wang, S. S. J. Sung, R. Sharma, C. Kannapell, W. Han, Q. Wang, A. Davidson, F. Gaskin, and S. M. Fu

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Autoimmunity to Vimentin and Lupus Nephritis, A. Davidson

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Smoking as a risk factor for the radiological severity of rheumatoid arthritis: a study on six cohorts, D. P. C. de Rooy, J. A. B. van Nies, M. C. Kapetanovic, H. Kristjansdottir, M. L. E. Andersson, K. Forslind, Dmfm van der Heijde, P. K. Gregersen, E. Lindqvist, A. H. M. van der Helm-van Mil, and +3 additional authors

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A genetic variant in the region of MMP-9 is associated with serum levels and progression of joint damage in rheumatoid arthritis, D. P. C. de Rooy, A. Zhernakova, R. Tsonaka, A. Willemze, B. A. S. Kurreeman, G. Trynka, L. van Toorn, R. E. M. Toes, P. K. Gregersen, A. H. M. van der Helm-van Mil, and +2 additional authors

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Sepsis: Current Dogma and New Perspectives, C. S. Deutschman and K. J. Tracey

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Letter from Incoming Editor in Chief of Molecular Medicine, Dr. Betty Diamond, B. Diamond

Patterns of variation influencing antipsychotic treatment outcomes in South African first-episode schizophrenia patients, B. I. Drogemoller, D. J. Niehaus, B. Chiliza, L. van der Merwe, L. Asmal, A. K. Malhotra, G. E. Wright, R. Emsley, and L. Warnich

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Can newly developed, rapid immunochromatographic antigen detection tests be reliably used for the laboratory diagnosis of influenza virus infections?, J. J. Dunn and C. C. Ginocchio

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Reply: Evidence against volume conduction to explain normal MEPs in muscles with low motor power in SCI, D. J. Edwards, M. Cortes, G. W. Thickbroom, A. Rykman, A. Pascual-Leone, and B. T. Volpe

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Expanding the genetics of huntingtonism, A. Feigin and K. Talbot

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The SORL1 gene and convergent neural risk for Alzheimer's disease across the human lifespan, D. Felsky, P. Szeszko, L. Yu, W. G. Honer, P. L. De Jager, J. A. Schneider, A. K. Malhotra, T. Lencz, T. Ikuta, A. N. Voineskos, and +7 additional authors

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Effects of aripiprazole once-monthly on domains of personal and social performance: Results from 2 multicenter, randomized, double-blind studies, W. W. Fleischhacker, R. A. Baker, A. Eramo, R. Sanchez, L. F. Tsai, T. Peters-Strickland, P. P. Perry, R. D. McQuade, B. R. Johnson, W. H. Carson, and J. M. Kane