Submissions from 2018
Evaluation and Management of Concussion in Young Athletes, J. Kosoy and R. Feinstein
CT Imaging of Emergent Renal Conditions, K. Kothari and J. J. Hines
Longitudinal evaluation of diffusion tensor imaging and cognition in systemic lupus erythematosus, E. Kozora, C. M. Filley, D. Erkan, A. M. Uluğ, A. Vo, G. Ramon, A. Burleson, R. D. Zimmerman, and M. D. Lockshin
Improving the Power of the American Society of Anesthesiology Classification System to Risk Stratify Vascular Surgery Patients Based on National Surgical Quality Improvement Project–Defined Functional Status, A. I. Kraev, J. McGinn, Y. Etkin, J. W. Turner, and G. S. Landis
Quality of web-based family-building information for LGBTQ individuals, F. M. Kreines, A. Farr, F. A. Chervenak, and A. Grunebaum
Mesalamine Associated Bradycardia., M. Krzyzak, A. Gupta, E. Antonov, and S. M. Mulrooney
Anticholinergic Toxicity Secondary to Overuse of Topricin Cream, a Homeopathic Medication., M. Krzyzak, A. Regina, R. C. Jesin, L. Deeb, E. Steinberg, and N. Majlesi
Cyclical cardiorenal syndrome in late-stage kidney disease, B. Ku and S. Fishbane
Intracranial electrophysiology reveals reproducible intrinsic functional connectivity within human brain networks, A. Kucyi, J. Schrouff, S. Bickel, B. L. Foster, J. M. Shine, and J. Parvizi
The relationship between in-session commitment language and daily self-reported commitment to reduce or abstain from drinking, A. Kuerbis, J. Houser, P. Amrhein, H. Treloar Padovano, and J. Morgenstern
Exploration of treatment matching of problem drinker characteristics to motivational interviewing and non-directive client-centered psychotherapy, A. Kuerbis, J. Houser, S. Levak, S. Shao, and J. Morgenstern
Comparing daily drivers of problem drinking among older and younger adults: An electronic daily diary study using smartphones, A. Kuerbis, H. Treloar Padovano, S. Shao, J. Houser, F. J. Muench, and J. Morgenstern
Financial planning and satisfaction across life domains among retired emergency physicians in the United States, G. J. Kuhn, C. A. Marco, M. N. Mallory, M. Blanda, J. A. Kaplan, S. M. Schneider, K. B. Joldersma, S. I. Martin, and E. K. Choo
superselective intraarterial cerebral infusion of cetuximab with blood brain barrier disruption combined with stupp protocol for newly diagnosed glioblastoma, K. O. Kulason, S. Chakraborty, C. G. Filippi, B. Pramanik, S. Fralin, K. Tan, A. Ray, R. Ortiz, A. Demopoulos, D. J. Langer, J. A. Boockvar, and +3 additional authors
Lesional Temporal Lobe Epilepsy: Beware the Deceitful "Panic Attack", K. O. Kulason, J. R. Schneider, R. Rahme, B. Pramanik, D. Chong, and J. A. Boockvar
Aortic root fibroelastoma causing cardiac ischemia, S. Kumar, R. Zeltser, and A. N. Makaryus
Role of Apolipoprotein L1 in Human Parietal Epithelial Cell Transition., V. Kumar, H. Vashistha, X. Lan, N. Chandel, K. Ayasolla, S. S.M. Shoshtari, R. Aslam, N. Paliwal, A. Malhotra, P. C. Singhal, and +7 additional authors
Inflammatory chemokine eotaxin-1 is correlated with age in heroin dependent patients under methadone maintenance therapy, H. W. Kuo, T. H. Liu, H. H. Tsou, Y. T. Hsu, S. C. Wang, C. P. Fang, C. C. Liu, A. C. Chen, and Y. L. Liu
Neonatal lung ultrasound exam guidelines, D. Kurepa, N. Zaghloul, L. Watkins, and J. Liu
The effect of fecal microbiota transplantation on psychiatric symptoms among patients with irritable bowel syndrome, functional diarrhea and functional constipation: An open-label observational study, S. Kurokawa, T. Kishimoto, S. Mizuno, T. Masaoka, M. Naganuma, K. C. Liang, M. Kitazawa, M. Nakashima, C. Shindo, M. Mimura, and +3 additional authors
Comparing phospholipid profiles of mitochondria and whole tissue: Higher PUFA content in mitochondria is driven by increased phosphatidylcholine unsaturation, C. E. Kuschner, J. Choi, T. Yin, K. Shinozaki, L. B. Becker, J. W. Lampe, and J. Kim
Epilepsy surgery in Panama: Establishment of a successful hybrid program as a model for small middle-income countries., R. Kuzniecky, C. Baez, G. Aranda, E. T. Hidalgo, A. Grover, C. Orillac, Zelenka, and H. L. Weiner
Local Immunotherapy for Malignancy: A Role for Brain Tumors?, K. Kwan, L. Falting, J. R. Schneider, and J. A. Boockvar
Quality of Life in Patients With Glioblastoma Treated With Tumor-Treating Fields, K. Kwan, J. R. Schneider, and J. A. Boockvar
Lessons Learned Using a High-Definition 3-Dimensional Exoscope for Spinal Surgery., K. Kwan, J. R. Schneider, V. Du, L. Falting, J. A. Boockvar, J. Oren, M. Levine, and D. J. Langer
Targeting Epidermal Growth Factor Receptors in Recurrent Glioblastoma Via a Novel Epithelial Growth Factor Receptor-Conjugated Nanocell Doxorubicin Delivery System, K. Kwan, J. R. Schneider, A. Kobets, and J. A. Boockvar
Response to Perrella et al, P. Y. Kwo, M. L. Shiffman, and D. E. Bernstein
The cochrane review conclusion for Hepatitis C DAA therapies is wrong, P. Y. Kwo, M. L. Shiff, and D. E. Bernstein
A primary breast cancer with distinct foci of estrogen receptor-alpha positive and negative cells derived from the same clonal origin as revealed by whole exome sequencing, K. Kyker-Snowman, B. Erlanger Avigdor, M. Nasim, A. Cimino-Mathews, S. J. Wheelan, P. Argani, and B. H. Park
Comorbidity of chronic somatic diseases in patients with psychotic disorders and their influence on 4-year outcomes of integrated care treatment (ACCESS II study), M. Lambert, F. Ruppelt, A. Siem, A. C. Rohenkohl, V. Kraft, D. Luedecke, M. Sengutta, R. Schroeter, C. U. Correll, D. Schoettle, and +4 additional authors
Early detection and integrated care for adolescents and young adults with severe psychotic disorders: rationales and design of the Integrated Care in Early Psychosis Study (ACCESS III), M. Lambert, D. Schoettle, M. Sengutta, F. Ruppelt, A. Rohenkohl, D. Luedecke, L. A. Nawara, B. Galling, C. U. Correll, A. Karow, and +22 additional authors
Multi-Trait Analysis of GWAS and Biological Insights Into Cognition: A Response to Hill (2018), M. Lam, J. W. Trampush, J. Yu, E. Knowles, S. Djurovic, I. Melle, K. Sundet, P. DeRosse, A. K. Malhotra, T. Lencz, and +51 additional authors
Effect of compression waveform and resuscitation duration on blood flow and pressure in swine: One waveform does not optimally serve, J. W. Lampe, T. Yin, G. Bratinov, C. L. Kaufman, R. A. Berg, A. Venema, and L. B. Becker
Cpx-351 (cytarabine and daunorubicin) liposome for injection versus conventional cytarabine plus daunorubicin in older patients with newly diagnosed secondary acute myeloid leukemia, J. E. Lancet, G. L. Uy, J. E. Cortes, L. F. Newell, T. L. Lin, E. K. Ritchie, R. K. Stuart, S. A. Strickland, J. E. Kolitz, B. C. Medeiros, and +11 additional authors
End-Tidal Carbon Dioxide Use for Tracheal Intubation: Analysis from the National Emergency Airway Registry for Children (NEAR4KIDS) Registry, M. L. Langhan, B. L. Emerson, S. Nett, M. Pinto, I. Harwayne-Gidansky, K. J. Rehder, C. Krawiec, K. Meyer, S. Gangadharan, A. Nishisaki, and +10 additional authors
Nicotine enhances mesangial cell proliferation and fibronectin production in high glucose milieu via activation of Wnt/beta-catenin pathway, X. Lan, H. Wen, R. Aslam, S. S. Shoshtari, A. Mishra, V. Kumar, H. Wang, G. Wu, A. Malhotra, P. C. Singhal, and +1 additional author
Huntingtin-interacting protein 1 (HIP1) regulates arthritis severity and synovial fibroblast invasiveness by altering PDGFR and Rac1 signalling, T. Laragione, M. Brenner, A. Lahiri, E. Gao, C. Harris, and P. S. Gulko
The pharmacological management of metabolic syndrome, J. R. Larsen, L. Dima, C. U. Correll, and P. Manu
Pre-close technique of percutaneous closure for delayed hemostasis of large-bore femoral sheaths, K. Lata, A. Kaki, C. Grines, N. Blank, M. Elder, and T. Schreiber
Day-case surgery is possible in the majority of men undergoing transurethral resection of the prostate – a report on over 1000 cases, L. Lavan, G. Kyriazis, D. Mbiabjeu, R. Gormley, S. Hall, R. Robinson, and D. Hodgson
Baseline Characteristics of the Vitamin D and Type 2 Diabetes (D2d) Study: A Contemporary Prediabetes Cohort That Will Inform Diabetes Prevention Efforts, E. S. LeBlanc, R. E. Pratley, B. Dawson-Hughes, M. A. Staten, P. R. Sheehan, M. R. Lewis, A. Peters, S. H. Kim, E. P. Liao, A. G. Pittas, and +16 additional authors
Spontaneous coronary artery dissection (SCAD): The underdiagnosed cardiac condition that plagues women, S. Lebrun and R. M. Bond
Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals, J. J. Lee, R. Wedow, A. Okbay, E. Kong, O. Maghzian, M. Zacher, A. N. Tuan, T. Lencz, A. K. Malhotra, D. Cesarini, and +67 additional authors
Multicenter Registry of Real-World Patients with Severely Calcified Coronary Lesions Undergoing Orbital Atherectomy: 1-Year Outcomes, M. S. Lee, E. Shlofmitz, A. Goldberg, and R. Shlofmitz
Impact of the Use of Intravascular Imaging on Patients Who Underwent Orbital Atherectomy, M. S. Lee, E. Shlofmitz, J. Kong, G. Lluri, P. K. Srivastava, and R. Shlofmitz
Outcomes of patients with severely calcified aorto-ostial coronary lesions who underwent orbital atherectomy, M. S. Lee, E. Shlofmitz, J. Kong, P. K. Srivastava, S. Al Yaseen, F. A. Sosa, M. Gallant, and R. Shlofmitz
One-Year Outcomes of Orbital Atherectomy of Long, Diffusely Calcified Coronary Artery Lesions, M. S. Lee, E. Shlofmitz, G. Lluri, K. W. Park, J. Hollowed, and R. Shlofmitz
Orbital Atherectomy of Severely Calcified Unprotected Left Main Coronary Artery Disease: One-Year Outcomes, M. S. Lee, E. Shlofmitz, K. W. Park, A. Goldberg, A. Jeremias, and R. Schlofmitz
Outcomes of orbital atherectomy in severely calcified small (2.5 mm) coronary artery vessels, M. S. Lee, E. Shlofmitz, and R. Shlofmitz
Procedural and long-term ischemic outcomes of tight subtotal occlusions treated with orbital atherectomy: An ORBIT II subanalysis., M. S. Lee, R. A. Shlofmitz, E. Shlofmitz, A. N. Behrens, G. Revtyak, B. J. Martinsen, and J. W. Chambers
Orbital atherectomy for the treatment of small (2.5 mm) severely calcified coronary lesions: ORBIT II sub-analysis, M. S. Lee, R. A. Shlofmitz, E. Shlofmitz, P. K. Srivastava, J. Kong, C. Grines, G. Revytak, and J. W. Chambers
The Role of Objectively Measured, Altered Physical Activity Patterns for Body Mass Index Change during Inpatient Treatment in Female Patients with Anorexia Nervosa, C. S. Lehmann, T. Hofmann, U. Elbelt, M. Rose, C. U. Correll, A. Stengel, and V. Haas
American views of Sir Victor Horsley in the era of Cushing., K. R. Lehner and M. Schulder
Reply to: Fluid Responsiveness: Goal-Directed Care or Resuscitative Guide to Salt Water Drowning?, D. E. Leisman, M. E. Doerfler, S. M. Schneider, J. A. D'Amore, and J. K. D'Angelo
Predictors, Prevalence, and Outcomes of Early Crystalloid Responsiveness Among Initially Hypotensive Patients With Sepsis and Septic Shock, D. E. Leisman, M. E. Doerfler, S. M. Schneider, K. D. Masick, J. A. D'Amore, and J. K. D'Angelo
Multidisciplinary Approach to Enhancing Safety and Care for Pediatric Behavioral Health Patients in Acute Medical Settings, G. Lelonek, D. Crook, M. Tully, K. Trufelli, L. Blitz, and S. C. Rogers
High-depth whole genome sequencing of an Ashkenazi Jewish reference panel: enhancing sensitivity, accuracy, and imputation, T. Lencz, J. Yu, C. Palmer, S. Carmi, D. Ben-Avraham, N. Barzilai, S. Bressman, A. Darvasi, J. H. Cho, I. Pe'er, and +10 additional authors
Palliative Care in New York State Nursing Homes: A Descriptive Study, P. E. Lester, F. Kawai, L. Rodrigues, J. Lolis, D. Martins-Welch, A. Shalshin, M. J. Fazzari, and C. X. Pan
Activity restriction and risk of preterm delivery, H. I. Levin, A. Sciscione, C. V. Ananth, D. Drassinower, S. G. Obican, and R. J. Wapner
A case of primary squamous cell carcinoma of the gallbladder with local invasion of the liver and peritoneum, and metastasis to the omentum., A. C.J. Levy, F. Casalduc-Coca, S. Asiry, and A. Goodman
Nimodipine for the treatment of otolaryngic indications, Z. D. Levy, H. Shafeeq, and J. H. Sin
Histopathologic characteristics of biopsies from dogs undergoing surgery with concurrent gross splenic and hepatic masses: 125 cases (2012-2016), F. J. Leyva, C. A. Loughin, C. W. Dewey, D. J. Marino, M. Akerman, and M. L. Lesser
Long-Term Outcomes of Total Exudative Retinal Detachments in Stage 3B Coats Disease, A. S. Li, A. Capone, M. T. Trese, J. E. Sears, A. Kychenthal, I. De la Huerta, and P. J. Ferrone
Correction: First results on survival from a large Phase 3 clinical trial of an autologous dendritic cell vaccine in newly diagnosed glioblastoma [J Transl Med., 16, (2018) (142)] DOI: 10.1186/s12967-018-1507-6, L. M. Liau, K. Ashkan, D. D. Tran, J. L. Campian, J. E. Trusheim, C. S. Cobbs, J. A. Heth, M. Salacz, M. Schulder, M. L. Bosch, and +10 additional authors
Correction to: First results on survival from a large Phase 3 clinical trial of an autologous dendritic cell vaccine in newly diagnosed glioblastoma, L. M. Liau, K. Ashkan, D. D. Tran, J. L. Campian, J. E. Trusheim, C. S. Cobbs, J. A. Heth, M. Salacz, M. Schulder, M. L. Bosch, and +59 additional authors
First results on survival from a large Phase 3 clinical trial of an autologous dendritic cell vaccine in newly diagnosed glioblastoma, L. M. Liau, K. Ashkan, D. D. Tran, J. L. Campian, J. E. Trusheim, C. S. Cobbs, J. A. Heth, M. Salacz, M. Schulder, M. L. Bosch, and +59 additional authors
Identifying Advanced Illness Patients in the Emergency Department and Having Goals-of-Care Discussions to Assist with Early Hospice Referral, T. Liberman, A. Kozikowski, N. Kwon, B. Emmert, M. Akerman, and R. Pekmezaris
Part II: Minimum Quality Threshold in Pre-Clinical Sepsis Studies (MQTiPSS) for Types of Infections and Organ Dysfunction Endpoints., C. Libert, A. Ayala, M. Bauer, J. Cavaillon, C. Deutschman, C. Frostell, S. Knapp, A. V. Kozlov, P. Wang, D. G. Remick, and +1 additional author
The development of a Biobank of cancer tissue samples from World Trade Center responders, W. Lieberman-Cribbin, S. Tuminello, C. Gillezeau, M. Van Gerwen, R. Brody, M. Donovan, and E. Taioli
Controversies and Challenges of Ventricular Assist Device Therapy, B. Lima, A. Bansal, J. Abraham, J. D. Rich, S. S. Lee, B. Soleimani, J. N. Katz, A. Kilic, J. S. Young, S. M. Joseph, and +1 additional author
The impact of unfractionated heparin or bivalirudin on patients with stable coronary artery disease undergoing percutaneous coronary intervention, F. V. Lima, L. Gruberg, U. Aslam, M. Ramgadoo, K. Clase, A. Trevisan, and A. Jeremias
Left ventricular end diastolic pressure and contrast-induced acute kidney injury in patients with acute coronary syndrome undergoing percutaneous coronary intervention, F. V. Lima, S. Singh, P. B. Parikh, and L. Gruberg
Therapeutic Approaches to Secondary Fracture Prevention in High Risk Populations: Current Recommendations and Advances, H. Lim, M. Chamblain, B. Wong, and S. Raghavan
Risk Factors for the Development of Nonalcoholic Fatty Liver Disease/Nonalcoholic Steatohepatitis, Including Genetics, H. W. Lim and D. E. Bernstein
An elderly patient's complete response to steroid therapy for collagenous gastritis, H. Lim, B. Y. Wong, D. Elkowitz, and K. Sultan
The Effect of Early-Life Environmental Exposures on Disease Phenotype and Clinical Course of Crohn’s Disease in Children, L. Lindoso, K. Mondal, S. Venkateswaran, H. K. Somineni, C. Ballengee, T. D. Walters, A. Griffiths, J. D. Noe, J. Markowitz, A. N. Ananthakrishnan, and +27 additional authors
Is 30-Day Posthospitalization Mortality Lower Among Racial/Ethnic Minorities?: A Reexamination, M. Lin, N. R. Kressin, M. K. Paasche-Orlow, E. J. Kim, L. Lopez, J. E. Rosen, and A. D. Hanchate
Identification of ethyl pyruvate as a NLRP3 inflammasome inhibitor that preserves mitochondrial integrity, S. Li, F. Liang, K. Kwan, Y. Tang, X. Wang, Y. Tang, H. Yang, S. S. Chavan, H. Wang, K. J. Tracey, and +3 additional authors
Glucocorticoid use and factors associated with variability in this use in the Systemic Lupus International Collaborating Clinics Inception Cohort, J. Little, B. Parker, M. Lunt, J. G. Hanly, M. B. Urowitz, A. E. Clarke, J. Romero-Diaz, C. Aranow, M. Mackay, I. N. Bruce, and +32 additional authors
Transcatheter aortic valve replacement in patients with severe mitral or tricuspid regurgitation at extreme risk for surgery, S. H. Little, J. J. Popma, N. S. Kleiman, G. M. Deeb, T. G. Gleason, S. J. Yakubov, S. Checuti, A. Hartman, S. Katz, M. J. Reardon, and +11 additional authors
Overexpression of β1 integrin contributes to polarity reversal and a poor prognosis of breast invasive micropapillary carcinoma, B. Liu, X. Zheng, F. Meng, Y. Han, Y. Song, F. Liu, S. Li, L. Zhang, X. Zhang, L. Fu, and +1 additional author
APBB2 is associated with amphetamine use and plasma beta-amyloids in patients receiving methadone maintenance treatment, C. C. Liu, C. P. Fang, T. H. Liu, H. W. Kuo, S. C. Liu, S. C. Wang, A. C. Chen, and Y. L. Liu
Return to Work After Anatomic Total Shoulder Arthroplasty for Patients 55 Years and Younger at Average 5-Year Follow-up., J. N. Liu, G. H. Garcia, A. C. Wong, A. Sinatro, H. H. Wu, D. M. Dines, R. F. Warren, and L. V. Gulotta
Return to sport after shoulder arthroplasty: a systematic review and meta-analysis, J. N. Liu, M. E. Steinhaus, G. H. Garcia, B. Chang, K. Fields, D. M. Dines, R. F. Warren, and L. V. Gulotta
HO-1hipatrolling monocytes protect against vaso-occlusion in sickle cell disease, Y. Liu, F. Jing, W. Yi, A. Mendelson, P. Shi, R. Walsh, D. F. Friedman, C. Minniti, D. Manwani, K. Yazdanbakhsh, and +1 additional author
Phosphoglycerate mutase 1 is highly expressed in C6 glioma cells and human astrocytoma, Z. Liu, J. Ding, C. Du, N. Xu, E. Wang, J. Li, Y. Wang, and J. Yu
Connexin 43 Hemichannel as a Novel Mediator of Sterile and Infectious Inflammatory Diseases, W. Li, W. Chen, S. Zhu, M. He, G. Ma, Y. Al-Abed, H. Yang, K. J. Tracey, P. Wang, J. D'Angelo, H. Wang, and +4 additional authors
Precise pathologic diagnosis and individualized treatment improve the outcomes of invasive micropapillary carcinoma of the breast: A 12-year prospective clinical study, W. Li, Y. Han, C. Wang, X. Guo, B. Shen, F. Liu, C. Jiang, Y. Li, X. Zhang, L. Fu, and +7 additional authors
Lung epithelial cell-derived IL-25 negatively regulates LPS-induced exosome release from macrophages, Z. G. Li, M. J. Scott, T. Brzóska, P. Sundd, Y. H. Li, T. R. Billiar, M. A. Wilson, P. Wang, and J. Fan
Composite Facial Volumization with Calcium Hydroxylapatite (CaHA) for the Treatment of Aging, Z. P. Lorenc, L. M. Bass, R. Fitzgerald, D. J. Goldberg, and M. H. Graivier
Physiochemical Characteristics of Calcium Hydroxylapatite (CaHA), Z. P. Lorenc, L. M. Bass, R. Fitzgerald, D. J. Goldberg, and M. H. Graivier
Focused update of expert consensus statement: Use of invasive assessments of coronary physiology and structure: A position statement of the society of cardiac angiography and interventions, A. Lotfi, J. E. Davies, W. F. Fearon, C. L. Grines, M. J. Kern, and L. W. Klein
Case series supporting heme detoxification via therapeutic plasma exchange in acute multiorgan failure syndrome resistant to red blood cell exchange in sickle cell disease, J. E. Louie, C. J. Anderson, K. Fayaz M. Fomani, A. Henry, T. Killeen, N. Mohandas, K. Yazdanbakhsh, J. D. Belcher, G. M. Vercellotti, and P. A. Shi
ACR Appropriateness Criteria®Breast Implant Evaluation, A. P. Lourenco, L. Moy, P. Baron, A. D. Didwania, R. M. diFlorio, S. L. Heller, A. I. Holbrook, A. A. Lewin, N. S. Vincoff, M. S. Newell, and +6 additional authors
A 6-month, multicenter, open-label study of fixed dose naproxen/esomeprazole in adolescent patients with juvenile idiopathic arthritis, D. J. Lovell, J. A. Dare, M. Francis-Sedlak, J. Ball, B. D. LaMoreaux, E. Von Scheven, A. Reinhardt, R. Jerath, B. Gottlieb, R. J. Holt, and +6 additional authors
Risk, Timing, and Predictors of Disease Flare After Discontinuation of Anti–Tumor Necrosis Factor Therapy in Children With Polyarticular Forms of Juvenile Idiopathic Arthritis With Clinically Inactive Disease, D. J. Lovell, A. L. Johnson, B. Huang, B. S. Gottlieb, P. W. Morris, Y. Kimura, K. Onel, S. C. Li, B. A. Eberhard, E. H. Giannini, and +34 additional authors
Cognitive and visual diagnostic errors in dermatology: part 1, E. J. Lowenstein and R. Sidlow
Diagnostic heuristics in dermatology, part 2: metacognition and other fixes, E. J. Lowenstein and R. Sidlow
Credentialing of hospitalists in ultrasound-guided bedside procedures: A position statement of the society of hospital medicine, B. P. Lucas, D. M. Tierney, T. P. Jensen, R. Dancel, J. Cho, M. El-Barbary, R. Franco-Sadud, N. J. Soni, P. Mayo, V. Tayal, and +25 additional authors
Histone H3K36M mutation and trimethylation patterns in chondroblastoma., C. Lu, D. Ramirez, S. Hwang, A. Jungbluth, D. Frosina, P. Ntiamoah, J. Healey, G. Zhu, W. Chen, M. Hameed, and +1 additional author