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Submissions from 2018

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PDZ-RhoGEF Is a Signaling Effector for TROY-Induced Glioblastoma Cell Invasion and Survival, Z. Ding, H. Dhruv, A. Kwiatkowska-Piwowarczyk, R. Ruggieri, J. Kloss, M. Symons, P. Pirrotte, J. M. Eschbacher, N. L. Tran, and J. C. Loftus

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Breathing above the brain stem: volitional control and attentional modulation in humans, J. L. Herrero, S. Khuvis, E. Yeagle, M. Cerf, and A. D. Mehta

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Identification of cytokine-specific sensory neural signals by decoding murine vagus nerve activity, T. P. Zanos, H. A. Silverman, T. Levy, T. Tsaava, E. Battinelli, P. W. Lorraine, J. M. Ashe, S. S. Chavan, K. J. Tracey, and C. E. Bouton

Submissions from 2017

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Repurposing Mebendazole as a Replacement for Vincristine for the Treatment of Brain Tumors, M. De Witt, A. Gamble, D. Hanson, D. Markowitz, C. Powell, S. Al Dimassi, M. Atlas, J. Boockvar, R. Ruggieri, and M. Symons

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Microtubule-targeting agents can sensitize cancer cells to ionizing radiation by an interphase-based mechanism, D. Markowitz, G. Ha, R. Ruggieri, and M. Symons

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Therapeutic Effects of Doxycycline on the Quality of Repaired and Unrepaired Achilles Tendons, Q. T. Nguyen, J. B. Norelli, A. Graver, C. Ekstein, J. Schwartz, F. Chowdhury, M. C. Drakos, D. A. Grande, and N. O. Chahine

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Colony Stimulating Factor-1 Receptor Inhibitors-A 4 for 1 Deal in the Desire to Improve Glioma Radiotherapy, B. Skeie, R. Ruggieri, J. A. Boockvar, and M. Symons

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Hippocampal-sparing and target volume coverage in treating 3 to 10 brain metastases: A comparison of Gamma Knife, single-isocenter VMAT, CyberKnife, and TomoTherapy stereotactic radiosurgery., I. Zhang, J. Antone, J. Li, S. Saha, A. C. Riegel, L. Vijeh, J. Lauritano, M. Marrero, S. Salas, M. Schulder, H. Zinkin, A. Goenka, and J. Knisely

Submissions from 2016

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"Pushing the envelope in neurosurgery": dilemma of the appropriate indications, H. Abou Al-Shaar, M. A. Labib, and A. R. Dehdashti

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Decompressive Craniectomy for Severe Traumatic Brain Injury: A Systematic Review, E. J. Barthelemy, M. Melis, E. Gordon, J. S. Ullman, and I. M. Germano

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Neuro-oncology biotech industry progress report, S. Chakraborty, I. Bodhinayake, A. Chiluwal, D. J. Langer, R. Ruggieri, M. Symons, and J. A. Boockvar

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Supratentorial Neurenteric Cysts: Case Series and Review of Pathology, Imaging, and Clinical Management, S. Chakraborty, F. Priamob, T. Lovena, J. Li, S. Insinga, and M. Schulder

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Seizure burden in subarachnoid hemorrhage: "Time is brain" as well!, G. Kapinos and J. G. Silva Latorre

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Radioresistance of Brain Tumors, K. Kelley, J. Knisely, M. Symons, and R. Ruggieri

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To the editor: Radiation plus Chemotherapy in Low-Grade Glioma, J. Knisely and M. Schulder

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Time-delayed contrast-enhanced MRI improves detection of brain metastases and apparent treatment volumes, M. Kushnirsky, V. Nguyen, J. S. Katz, J. Steinklein, L. Rosen, C. Warshall, M. Schulder, and J. P. Knisely

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Ventriculoperitoneal Shunt Infection with Mycobacterium abscessus: A Rare Cause of Ventriculitis, Z. D. Levy, V. Du, A. Chiluwal, D. J. Chalif, and D. E. Ledoux

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Pharmacological Inhibition of the Protein Kinase MRK/ZAK Radiosensitizes Medulloblastoma, D. Markowitz, C. Powell, N. L. Tran, M. E. Berens, T. C. Ryken, L. Rosen, S. Sun, M. Symons, Y. Al-Abed, R. Ruggieri, and +2 additional authors

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Curcumin changes the polarity of tumor-associated microglia and eliminates glioblastoma, S. Mukherjee, J. Baidoo, A. Fried, D. Atwi, S. Dolai, J. Boockvar, M. Symons, R. Ruggieri, K. Raja, and P. Banerjee

Outcomes in Patients with Vestibular Schwannoma after Subtotal Resection and Adjuvant Radiosurgery, H. Radwan, M. Bruce Eisenberg, J. P. S. Knisely, M. M. Ghaly, and M. Schulder

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Cytokine-specific Neurograms in the Sensory Vagus Nerve., B. E. Steinberg, H. A. Silverman, M. K. Gunasekaran, T. Tsaava, E. Battinelli, A. Stiegler, C. E. Bouton, S. S. Chavan, J. J. Tracey, P. T. Huerta, and +1 additional author

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Neurosurgeons' Critical Role in Managing Traumatic Brain Injury, J. S. Ullman, S. D. Timmons, and A. B. Valadka

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High-Density Lipoprotein (HDL) Counter-Regulates Serum Amyloid A (SAA)-Induced sPLA(2)-IIE and sPLA(2)-V Expression in Macrophages, S. Zhu, Y. Wang, W. Chen, W. Li, A. Wang, J. Li, H. Yang, K. J. Tracey, J. D'Angelo, H. Wang, and +2 additional authors

Submissions from 2015

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Rare cause of trigeminal neuralgia: Meckel's cave meningocele, A. Alobaid, T. Schaeffer, J. Virojanapa, and A. Dehdashti

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Celecoxib inhibits Ewing sarcoma cell migration via actin modulation, C. A. Behr, A. J. Hesketh, M. Barlow, R. D. Glick, M. Symons, B. M. Steinberg, and S. Z. Soffer

Synaptojanin 2 is a druggable mediator of metastasis and the gene is overexpressed and amplified in breast cancer, N. Ben-Chetrit, D. Chetrit, A. Abdul-Hai, T. Itkin, S. Carvalho, H. Cohen-Dvashi, W. J. Koestler, M. Symons, M. Ehrlich, Y. Yarden, and +21 additional authors

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Comparison of indocyanine green fluorescent angiography to digital subtraction angiography in brain arteriovenous malformation surgery, C. J. Bilbao, T. Bhalla, S. Dalal, H. Patel, and A. R. Dehdashti

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Repurposing mebendazole for the treatment of medulloblastoma, I. Bodhinayake, M. Symons, and J. A. Boockvar

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Prolonged mechanical ventilation is associated with pulmonary complications, increased length of stay, and unfavorable discharge destination among patients with subdural hematoma, K. M. Busl, B. Ouyang, T. A. Boland, S. Pollandt, and R. E. Temes

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Evaluation of Outcomes After Endoscopic Endonasal Surgery for Large and Giant Pituitary Macroadenoma: A Retrospective Review of 39 Consecutive Patients, J. D. Chabot, S. Chakraborty, G. Imbarrato, and A. R. Dehdashti

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Sepsis: a roadmap for future research, J. Cohen, J. L. Vincent, N. K. Adhikari, F. R. Machado, S. Giulieri, J. Delaloye, S. Opal, K. Tracey, T. van der Poll, E. Pelfrene, and +3 additional authors

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Ophthalmic artery aneurysm treated by surgical clipping and balloon-assisted temporary carotid occlusion, A. R. Dehdashti

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Surgical treatment of a large ruptured internal carotid artery bifurcation aneurysm, A. R. Dehdashti

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The suboccipital midline approach to foramen magnum meningiomas; feasible, but is it optimal?, A. R. Dehdashti

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A New Tool in Defining Disease Progression in Glioblastoma, M. E. De Witt and J. A. Boockvar

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Variables associated with the decreased risk of intraventricular haemorrhage in a large sample of neonates with respiratory distress syndrome, H. Doshi, Y. Moradiya, P. Roth, and J. Blau

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Combining task-evoked and spontaneous activity to improve pre-operative brain mapping with fMRI, M. D. Fox, T. Qian, J. R. Madsen, D. Wang, M. Ge, H. C. Zuo, D. M. Groppe, A. D. Mehta, B. Hong, H. Liu, and +1 additional author

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Toxin-Secreting Implantable Therapeutic Stem Cells, A. J. Gamble and J. A. Boockvar

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Awake Craniotomy in Arteriovenous Malformation Surgery: The Usefulness of Cortical and Subcortical Mapping of Language Function in Selected Patients, A. J. Gamble, S. G. Schaffer, D. J. Nardi, D. J. Chalif, J. Katz, and A. R. Dehdashti

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First-In-Human, Phase 1, Randomized, Dose-Escalation Trial with Recombinant Anti-IL-20 Monoclonal Antibody in Patients with Psoriasis, A. B. Gottlieb, J. G. Krueger, M. Sandberg Lundblad, M. Gothberg, and B. E. Skolnick

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Tight regulation between cell survival and programmed cell death in GBM stem-like cells by EGFR/GSK3b/PP2A signaling, D. B. Gursel, M. A. Banu, N. Berry, R. Marongiu, J. K. Burkhardt, K. Kobylarz, M. G. Kaplitt, S. Rafii, and J. A. Boockvar

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Laminar Profile and Physiology of the alpha Rhythm in Primary Visual, Auditory, and Somatosensory Regions of Neocortex, S. Haegens, A. Barczak, G. Musacchia, M. L. Lipton, A. D. Mehta, P. Lakatos, and C. E. Schroeder

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Galantamine Attenuates Type 1 Diabetes and Inhibits Anti-Insulin Antibodies in Non-Obese Diabetic Mice, W. M. Hanes, P. S. Olofsson, K. Kwan, L. K. Hudson, S. S. Chavan, V. A. Pavlov, and K. J. Tracey

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The Macrophage Inhibitor CNI-1493 Blocks Metastasis in a Mouse Model of Ewing Sarcoma through Inhibition of Extravasation, A. J. Hesketh, C. Maloney, C. A. Behr, M. C. Edelman, R. D. Glick, Y. Al-Abed, M. Symons, S. Z. Soffer, and B. M. Steinberg

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Notch receptor expression in human brain arteriovenous malformations, S. Hill-Felberg, H. H. Wu, S. A. Toms, and A. R. Dehdashti

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The Comparative Effectiveness of Specific Professional Educational Tools for Correcting Knowledge Gaps Among Practicing Neurosurgeons, B. L. Hoh, J. Curran, J. Rokicki, J. S. Ullman, B. R. Bendok, G. Rao, N. R. Selden, D. K. Resnick, and Z. Ghogawala

Redefining secondary injury after subarachnoid hemorrhage in light of multimodal advanced neuroimaging, intracranial and transcranial neuromonitoring: beyond vasospasm, G. Kapinos

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Extended endoscopic endonasal transclival clipping of posterior circulation aneurysms-an alternative to the transcranial approach, M. Labib and A. R. Dehdashti

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Single probe for real-time simultaneous monitoring of neurochemistry and direct-current electrocorticography, C. Li, K. Limnuson, Z. Wu, A. Amin, A. Narayan, E. V. Golanov, C. H. Ahn, J. A. Hartings, and R. K. Narayan

Evaluation of microelectrode materials for direct-current electrocorticography, C. Li, R. K. Narayan, P. M. Wu, N. Rajan, Z. Wu, N. Mehan, E. V. Golanov, C. H. Ahn, and J. A. Hartings

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Highly accurate thermal flow microsensor for continuous and quantitative measurement of cerebral blood flow, C. Li, P. M. Wu, Z. Wu, K. Limnuson, N. Mehan, C. Mozayan, E. V. Golanov, C. H. Ahn, J. A. Hartings, and R. K. Narayan

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DAMP Signaling is a Key Pathway Inducing Immune Modulation after Brain Injury, A. Liesz, A. Dalpke, E. Mracsko, D. J. Antoine, S. Roth, W. Zhou, H. Yang, P. P. Nawroth, K. J. Tracey, R. Veltkamp, and +4 additional authors

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Serum Amyloid A Stimulates PKR Expression and HMGB1 Release Possibly through TLR4/RAGE Receptors, W. Li, S. Zhu, J. Li, J. D'Amore, J. D'Angelo, H. Yang, P. Wang, K. J. Tracey, and H. Wang

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Regulation of post-translational modifications of HMGB1 during immune responses, B. Lu, Y. Tang, X. Zhao, D. Antoine, X. Xiao, H. Wang, U. Andersson, T. Billiar, and K. J. Tracey

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Inferiorly-Directed Posterior Cranial Vault Distraction for Treatment of Chiari Malformations, S. M. Lu, H. L. Rekate, N. Tanna, A. K. Kasabian, L. S. Leipziger, J. P. Bradley, and N. M. Bastidas

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Concurrent use of the Pipeline Embolization Device and coils for intracranial aneurysms: technique, safety, and efficacy, E. Nossek, D. J. Chalif, S. Chakraborty, K. Lombardo, K. S. Black, and A. Setton

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Forearm Cephalic Vein Graft for Short, "Middle"-Flow, Internal Maxillary Artery to Middle Cerebral Artery Bypass, E. Nossek, P. Costantino, D. J. Chalif, R. A. Ortiz, A. R. Dehdashti, and D. J. Langer

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Analysis of superiorly projecting anterior communicating artery aneurysms: anatomy, techniques, and outcome. A proposed classification system, E. Nossek, A. Setton, R. Karimi, A. R. Dehdashti, D. J. Langer, and D. J. Chalif

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Intracranial recordings reveal transient response dynamics during information maintenance in human cerebral cortex, N. Noy, S. Bickel, E. Zion-Golumbic, M. Harel, T. Golan, G. M. McKhann, R. R. Goodman, C. E. Schroeder, A. D. Mehta, R. Malach, and +2 additional authors

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Single-Pulse and Unidirectional Electrical Activation of the Cervical Vagus Nerve Reduces Tumor Necrosis Factor in Endotoxemia, P. S. Olofsson, Y.A. Levine, A. Caravaca, S. S. Chavan, V. A. Pavlov, M. Faltys, and K. J. Tracey

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Recidivism among ED super users after implementation of a pain protocol, B. Passarello, Z. Levy, B. Levine, M. Papas, and N. Jasani

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Fascicular Involvement of the Posterior Tibial Nerve as a Result of Perineural Ganglion Cyst at the Posterior Tibial Nerve in the Calf: A Case Report and Review of Literature, C. Patel, S. M. Vishnubhakat, and R. Narayan

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Neural circuitry and immunity, V. Pavlov and K. J. Tracey

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A unifying principle underlying the extracellular field potential spectral responses in the human cortex, E. Podvalny, N. Noy, M. Harel, S. Bickel, G. Chechik, C. E. Schroeder, A. D. Mehta, M. Tsodyks, and R. Malach

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Finally, open loop control of intracranial pressure in hydrocephalus, H. L. Rekate

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Xanomeline suppresses excessive pro-inflammatory cytokine responses through neural signal-mediated pathways and improves survival in lethal inflammation, M. Rosas-Ballina, S. I. Valdes-Ferrer, M. E. Dancho, M. Ochani, D. Katz, K. F. Cheng, P. S. Olofsson, S. S. Chavan, Y. Al-Abed, K. J. Tracey, and V. A. Pavlov

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Lumboatrial shunt in a patient with Crouzon syndrome complicated by pseudotumor cerebri, E. W. Sankey, M. H. Khattab, B. D. Elder, C. R. Goodwin, H. L. Rekate, and D. Rigamonti

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Isolated cortical vein thrombosis: case series, R. Singh, W. P. Cope, Z. Zhou, M. E. De Witt, J. A. Boockvar, and A. J. Tsiouris

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Progesterone in Traumatic Brain Injury REPLY, B. E. Skolnick, A. I. R. Maas, and R. K. Narayan

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Multiportal Combined Transorbital and Transnasal Endoscopic Resection of Fibrous Dysplasia, T. Tham, P. Costantino, M. Bruni, D. Langer, J. Boockvar, and P. Singh

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Approaching the Next Revolution? Evolutionary Integration of Neural and Immune Pathogen Sensing and Response, K. J. Tracey

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SHOCK MEDICINE, K. J. Tracey

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Delay in Arrival to Care in Perpetrator-Identified Nonaccidental Head Trauma: Observations and Outcomes, S. Vadivelu, D. Esernio-Jenssen, H. L. Rekate, R. K. Narayan, M. A. Mittler, and S. J. Schneider

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HMGB1 mediates anemia of inflammation in murine sepsis survivors, S. I. Valdes-Ferrer, J. Papoin, M. E. Dancho, L. P. S. Olofsson, J. Li, J. M. Lipton, P. Avancena, H. Yang, Y. R. Zou, S. S. Chavan, B. T. Volpe, S. Rivella, B. Diamond, B. M. Steinberg, L. Blanc, K. J. Tracey, and +2 additional authors

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Accuracy of the ABC/2 Score for Intracerebral Hemorrhage: Systematic Review and Analysis of MISTIE, CLEAR-IVH, and CLEAR III, A. J. Webb, N. L. Ullman, T. C. Morgan, J. Muschelli, J. Kornbluth, I. A. Awad, S. Mayo, M. Rosenblum, R. Narayan, D. F. Hanley, and +14 additional authors

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Developments in intervertebral disc disease research: pathophysiology, mechanobiology, and therapeutics, K. T. Weber, T. D. Jacobsen, R. Maidhof, J. Virojanapa, C. Overby, O. Bloom, S. Quraishi, M. Levine, and N. O. Chahine

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Exploratory study for identifying systemic biomarkers that correlate with pain response in patients with intervertebral disc disorders, K. T. Weber, S. Satoh, D. O. Alipui, J. Virojanapa, M. Levine, C. Sison, S. Quraishi, O. Bloom, and N. O. Chahine

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Stress Induces the Danger-Associated Molecular Pattern HMGB-1 in the Hippocampus of Male Sprague Dawley Rats: A Priming Stimulus of Microglia and the NLRP3 Inflammasome, M. D. Weber, M. G. Frank, K. J. Tracey, L. R. Watkins, and S. F. Maier

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HbSC Disease and Spontaneous Epidural Hematoma with Kernohan's Notch Phenomena, M. Yogarajah, C. C. Agu, B. Sivasambu, and M. A. Mittler

Submissions from 2014

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The functions of HMGB1 depend on molecular localization and post-translational modifications Introduction, U. Andersson, D. J. Antoine, and K. J. Tracey

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A Systematic Nomenclature for the Redox States of High Mobility Group Box (HMGB) Proteins, D. J. Antoine, H. E. Harris, U. Andersson, K. J. Tracey, and M. E. Bianchi

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Targeting a heterogeneous tumor: the promise of the interleukin-13 receptor alpha2, I. Bodhinayake, M. Ottenhausen, and J. A. Boockvar

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Results and risk factors for recurrence following endoscopic endonasal transsphenoidal surgery for pituitary adenoma, I. Bodhinayake, M. Ottenhausen, M. A. Mooney, K. Kesavabhotla, P. Christos, J. T. Schwarz, and J. A. Boockvar

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Farewell Statement from Dr. Cerami and Dr. Tracey as Outgoing Co-Editors in Chief of Molecular Medicine, A. Cerami and K. J. Tracey

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Nanocomposite Scaffold for Chondrocyte Growth and Cartilage Tissue Engineering: Effects of Carbon Nanotube Surface Functionalization, N. O. Chahine, N. M. Collette, C. B. Thomas, D. C. Genetos, and G. G. Loots

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Novel hydrogel application in minimally invasive surgical approaches to spontaneous intracranial hypotension. Report of 2 cases, C. M. Chai, M. A. Banu, W. Cobb, N. Mehta, L. Heier, and J. A. Boockvar

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Regulating innate immunity with dopamine and electroacupuncture, S. S. Chavan and K. J. Tracey

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Exemplar Selectivity Reflects Perceptual Similarities in the Human Fusiform Cortex, I. Davidesco, E. Zion-Golumbic, S. Bickel, M. Harel, D. M. Groppe, C. J. Keller, C. A. Schevon, G. M. McKhann, R. R. Goodman, G. Goelman, C. E. Schroeder, A. D. Mehta, and R. Malach

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Sepsis: Current Dogma and New Perspectives, C. S. Deutschman and K. J. Tracey

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Evoked Effective Connectivity of the Human Neocortex, L. Entz, E. Toth, C. J. Keller, S. Bickel, D. M. Groppe, D. Fabo, L. R. Kozak, L. Eross, I. Ulbert, and A. D. Mehta

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Prophylactic plastic surgery closure of neurosurgical scalp incisions reduces the incidence of wound complications in previously-operated patients treated with bevacizumab (Avastin(R)) and radiation, A. R. Golas, T. Boyko, T. H. Schwartz, P. E. Stieg, J. A. Boockvar, and J. A. Spector

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Conservative management of cavernous sinus cavernous hemangioma in pregnancy, J. S. Haber, K. Kesavabhotla, M. Ottenhausen, I. Bodhinayake, M. J. Dinkin, A. Z. Segal, Y. M. Lee, and J. A. Boockvar

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Flow-based evaluation of cerebral revascularization using near-infrared indocyanine green videoangiography, J. Januszewski, J. S. Beecher, D. J. Chalif, and A. R. Dehdashti

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Central cholinergic activation of a vagus nerve-to-spleen circuit alleviates experimental colitis, H. Ji, M. F. Rabbi, B. Labis, V. A. Pavlov, K. J. Tracey, and J. E. Ghia

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Sequestering HMGB1 via DNA-conjugated beads ameliorates murine colitis, Z. Ju, S. S. Chavan, M. Dancho, T. Tsaava, J. Li, B. Lu, Y. Al-Abed, J. Roth, K. J. Tracey, H. Yang, and +4 additional authors

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Intracellular Hmgb1 inhibits inflammatory nucleosome release and limits acute pancreatitis in mice, R. Kang; Q. Zhang; W. Hou; Z. Yan; R. Chen; J. Bonaroti; P. Bansal; T. R. Billiar; A. Tsung; Q. Wang; D. L. Bartlett; D. C. Whitcomb; E. B. Chang; X. Zhu; H. Wang; B. Lu; K. J. Tracey; L. Cao; X. G. Fan; M. T. Lotze; H. J., 3rd Zeh; and D. Tang

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Hypertensive crisis Reversible edema in leukoencephalopathy, retinopathy, now myelopathy?, G. Kapinos and P. C. Sanelli

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Corticocortical Evoked Potentials Reveal Projectors and Integrators in Human Brain Networks, C. J. Keller, C. J. Honey, L. Entz, S. Bickel, D. M. Groppe, E. Toth, I. Ulbert, F. A. Lado, and A. D. Mehta

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Mapping human brain networks with cortico-cortical evoked potentials, C. J. Keller, C. J. Honey, P. Megevand, L. Entz, I. Ulbert, and A. D. Mehta

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Enhancement of Achilles Tendon Repair Mediated by Matrix Metalloproteinase Inhibition via Systemic Administration of Doxycycline, M. W. Kessler, J. Barr, R. Greenwald, L. B. Lane, J. S. Dines, D. M. Dines, M. C. Drakos, D. A. Grande, and N. O. Chahine