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Submissions from 2015

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First-In-Human, Phase 1, Randomized, Dose-Escalation Trial with Recombinant Anti-IL-20 Monoclonal Antibody in Patients with Psoriasis, A. B. Gottlieb, J. G. Krueger, M. Sandberg Lundblad, M. Gothberg, and B. E. Skolnick

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Tight regulation between cell survival and programmed cell death in GBM stem-like cells by EGFR/GSK3b/PP2A signaling, D. B. Gursel, M. A. Banu, N. Berry, R. Marongiu, J. K. Burkhardt, K. Kobylarz, M. G. Kaplitt, S. Rafii, and J. A. Boockvar

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Laminar Profile and Physiology of the alpha Rhythm in Primary Visual, Auditory, and Somatosensory Regions of Neocortex, S. Haegens, A. Barczak, G. Musacchia, M. L. Lipton, A. D. Mehta, P. Lakatos, and C. E. Schroeder

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Galantamine Attenuates Type 1 Diabetes and Inhibits Anti-Insulin Antibodies in Non-Obese Diabetic Mice, W. M. Hanes, P. S. Olofsson, K. Kwan, L. K. Hudson, S. S. Chavan, V. A. Pavlov, and K. J. Tracey

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The Macrophage Inhibitor CNI-1493 Blocks Metastasis in a Mouse Model of Ewing Sarcoma through Inhibition of Extravasation, A. J. Hesketh, C. Maloney, C. A. Behr, M. C. Edelman, R. D. Glick, Y. Al-Abed, M. Symons, S. Z. Soffer, and B. M. Steinberg

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Notch receptor expression in human brain arteriovenous malformations, S. Hill-Felberg, H. H. Wu, S. A. Toms, and A. R. Dehdashti

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The Comparative Effectiveness of Specific Professional Educational Tools for Correcting Knowledge Gaps Among Practicing Neurosurgeons, B. L. Hoh, J. Curran, J. Rokicki, J. S. Ullman, B. R. Bendok, G. Rao, N. R. Selden, D. K. Resnick, and Z. Ghogawala

Redefining secondary injury after subarachnoid hemorrhage in light of multimodal advanced neuroimaging, intracranial and transcranial neuromonitoring: beyond vasospasm, G. Kapinos

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Extended endoscopic endonasal transclival clipping of posterior circulation aneurysms-an alternative to the transcranial approach, M. Labib and A. R. Dehdashti

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Single probe for real-time simultaneous monitoring of neurochemistry and direct-current electrocorticography, C. Li, K. Limnuson, Z. Wu, A. Amin, A. Narayan, E. V. Golanov, C. H. Ahn, J. A. Hartings, and R. K. Narayan

Evaluation of microelectrode materials for direct-current electrocorticography, C. Li, R. K. Narayan, P. M. Wu, N. Rajan, Z. Wu, N. Mehan, E. V. Golanov, C. H. Ahn, and J. A. Hartings

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Highly accurate thermal flow microsensor for continuous and quantitative measurement of cerebral blood flow, C. Li, P. M. Wu, Z. Wu, K. Limnuson, N. Mehan, C. Mozayan, E. V. Golanov, C. H. Ahn, J. A. Hartings, and R. K. Narayan

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DAMP Signaling is a Key Pathway Inducing Immune Modulation after Brain Injury, A. Liesz, A. Dalpke, E. Mracsko, D. J. Antoine, S. Roth, W. Zhou, H. Yang, P. P. Nawroth, K. J. Tracey, R. Veltkamp, and +4 additional authors

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Serum Amyloid A Stimulates PKR Expression and HMGB1 Release Possibly through TLR4/RAGE Receptors, W. Li, S. Zhu, J. Li, J. D'Amore, J. D'Angelo, H. Yang, P. Wang, K. J. Tracey, and H. Wang

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Regulation of post-translational modifications of HMGB1 during immune responses, B. Lu, Y. Tang, X. Zhao, D. Antoine, X. Xiao, H. Wang, U. Andersson, T. Billiar, and K. J. Tracey

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Inferiorly-Directed Posterior Cranial Vault Distraction for Treatment of Chiari Malformations, S. M. Lu, H. L. Rekate, N. Tanna, A. K. Kasabian, L. S. Leipziger, J. P. Bradley, and N. M. Bastidas

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Concurrent use of the Pipeline Embolization Device and coils for intracranial aneurysms: technique, safety, and efficacy, E. Nossek, D. J. Chalif, S. Chakraborty, K. Lombardo, K. S. Black, and A. Setton

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Forearm Cephalic Vein Graft for Short, "Middle"-Flow, Internal Maxillary Artery to Middle Cerebral Artery Bypass, E. Nossek, P. Costantino, D. J. Chalif, R. A. Ortiz, A. R. Dehdashti, and D. J. Langer

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Analysis of superiorly projecting anterior communicating artery aneurysms: anatomy, techniques, and outcome. A proposed classification system, E. Nossek, A. Setton, R. Karimi, A. R. Dehdashti, D. J. Langer, and D. J. Chalif

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Intracranial recordings reveal transient response dynamics during information maintenance in human cerebral cortex, N. Noy, S. Bickel, E. Zion-Golumbic, M. Harel, T. Golan, G. M. McKhann, R. R. Goodman, C. E. Schroeder, A. D. Mehta, R. Malach, and +2 additional authors

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Single-Pulse and Unidirectional Electrical Activation of the Cervical Vagus Nerve Reduces Tumor Necrosis Factor in Endotoxemia, P. S. Olofsson, Y.A. Levine, A. Caravaca, S. S. Chavan, V. A. Pavlov, M. Faltys, and K. J. Tracey

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Recidivism among ED super users after implementation of a pain protocol, B. Passarello, Z. Levy, B. Levine, M. Papas, and N. Jasani

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Fascicular Involvement of the Posterior Tibial Nerve as a Result of Perineural Ganglion Cyst at the Posterior Tibial Nerve in the Calf: A Case Report and Review of Literature, C. Patel, S. M. Vishnubhakat, and R. Narayan

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Neural circuitry and immunity, V. Pavlov and K. J. Tracey

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A unifying principle underlying the extracellular field potential spectral responses in the human cortex, E. Podvalny, N. Noy, M. Harel, S. Bickel, G. Chechik, C. E. Schroeder, A. D. Mehta, M. Tsodyks, and R. Malach

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Finally, open loop control of intracranial pressure in hydrocephalus, H. L. Rekate

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Xanomeline suppresses excessive pro-inflammatory cytokine responses through neural signal-mediated pathways and improves survival in lethal inflammation, M. Rosas-Ballina, S. I. Valdes-Ferrer, M. E. Dancho, M. Ochani, D. Katz, K. F. Cheng, P. S. Olofsson, S. S. Chavan, Y. Al-Abed, K. J. Tracey, and V. A. Pavlov

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Lumboatrial shunt in a patient with Crouzon syndrome complicated by pseudotumor cerebri, E. W. Sankey, M. H. Khattab, B. D. Elder, C. R. Goodwin, H. L. Rekate, and D. Rigamonti

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Isolated cortical vein thrombosis: case series, R. Singh, W. P. Cope, Z. Zhou, M. E. De Witt, J. A. Boockvar, and A. J. Tsiouris

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Progesterone in Traumatic Brain Injury REPLY, B. E. Skolnick, A. I. R. Maas, and R. K. Narayan

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Multiportal Combined Transorbital and Transnasal Endoscopic Resection of Fibrous Dysplasia, T. Tham, P. Costantino, M. Bruni, D. Langer, J. Boockvar, and P. Singh

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Approaching the Next Revolution? Evolutionary Integration of Neural and Immune Pathogen Sensing and Response, K. J. Tracey

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SHOCK MEDICINE, K. J. Tracey

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Delay in Arrival to Care in Perpetrator-Identified Nonaccidental Head Trauma: Observations and Outcomes, S. Vadivelu, D. Esernio-Jenssen, H. L. Rekate, R. K. Narayan, M. A. Mittler, and S. J. Schneider

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HMGB1 mediates anemia of inflammation in murine sepsis survivors, S. I. Valdes-Ferrer, J. Papoin, M. E. Dancho, L. P. S. Olofsson, J. Li, J. M. Lipton, P. Avancena, H. Yang, Y. R. Zou, S. S. Chavan, B. T. Volpe, S. Rivella, B. Diamond, B. M. Steinberg, L. Blanc, K. J. Tracey, and +2 additional authors

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Accuracy of the ABC/2 Score for Intracerebral Hemorrhage: Systematic Review and Analysis of MISTIE, CLEAR-IVH, and CLEAR III, A. J. Webb, N. L. Ullman, T. C. Morgan, J. Muschelli, J. Kornbluth, I. A. Awad, S. Mayo, M. Rosenblum, R. Narayan, D. F. Hanley, and +14 additional authors

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Developments in intervertebral disc disease research: pathophysiology, mechanobiology, and therapeutics, K. T. Weber, T. D. Jacobsen, R. Maidhof, J. Virojanapa, C. Overby, O. Bloom, S. Quraishi, M. Levine, and N. O. Chahine

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Exploratory study for identifying systemic biomarkers that correlate with pain response in patients with intervertebral disc disorders, K. T. Weber, S. Satoh, D. O. Alipui, J. Virojanapa, M. Levine, C. Sison, S. Quraishi, O. Bloom, and N. O. Chahine

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Stress Induces the Danger-Associated Molecular Pattern HMGB-1 in the Hippocampus of Male Sprague Dawley Rats: A Priming Stimulus of Microglia and the NLRP3 Inflammasome, M. D. Weber, M. G. Frank, K. J. Tracey, L. R. Watkins, and S. F. Maier

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HbSC Disease and Spontaneous Epidural Hematoma with Kernohan's Notch Phenomena, M. Yogarajah, C. C. Agu, B. Sivasambu, and M. A. Mittler

Submissions from 2014

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The functions of HMGB1 depend on molecular localization and post-translational modifications Introduction, U. Andersson, D. J. Antoine, and K. J. Tracey

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A Systematic Nomenclature for the Redox States of High Mobility Group Box (HMGB) Proteins, D. J. Antoine, H. E. Harris, U. Andersson, K. J. Tracey, and M. E. Bianchi

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Targeting a heterogeneous tumor: the promise of the interleukin-13 receptor alpha2, I. Bodhinayake, M. Ottenhausen, and J. A. Boockvar

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Results and risk factors for recurrence following endoscopic endonasal transsphenoidal surgery for pituitary adenoma, I. Bodhinayake, M. Ottenhausen, M. A. Mooney, K. Kesavabhotla, P. Christos, J. T. Schwarz, and J. A. Boockvar

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Farewell Statement from Dr. Cerami and Dr. Tracey as Outgoing Co-Editors in Chief of Molecular Medicine, A. Cerami and K. J. Tracey

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Nanocomposite Scaffold for Chondrocyte Growth and Cartilage Tissue Engineering: Effects of Carbon Nanotube Surface Functionalization, N. O. Chahine, N. M. Collette, C. B. Thomas, D. C. Genetos, and G. G. Loots

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Novel hydrogel application in minimally invasive surgical approaches to spontaneous intracranial hypotension. Report of 2 cases, C. M. Chai, M. A. Banu, W. Cobb, N. Mehta, L. Heier, and J. A. Boockvar

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Regulating innate immunity with dopamine and electroacupuncture, S. S. Chavan and K. J. Tracey

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Exemplar Selectivity Reflects Perceptual Similarities in the Human Fusiform Cortex, I. Davidesco, E. Zion-Golumbic, S. Bickel, M. Harel, D. M. Groppe, C. J. Keller, C. A. Schevon, G. M. McKhann, R. R. Goodman, G. Goelman, C. E. Schroeder, A. D. Mehta, and R. Malach

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Sepsis: Current Dogma and New Perspectives, C. S. Deutschman and K. J. Tracey

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Evoked Effective Connectivity of the Human Neocortex, L. Entz, E. Toth, C. J. Keller, S. Bickel, D. M. Groppe, D. Fabo, L. R. Kozak, L. Eross, I. Ulbert, and A. D. Mehta

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Prophylactic plastic surgery closure of neurosurgical scalp incisions reduces the incidence of wound complications in previously-operated patients treated with bevacizumab (Avastin(R)) and radiation, A. R. Golas, T. Boyko, T. H. Schwartz, P. E. Stieg, J. A. Boockvar, and J. A. Spector

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Conservative management of cavernous sinus cavernous hemangioma in pregnancy, J. S. Haber, K. Kesavabhotla, M. Ottenhausen, I. Bodhinayake, M. J. Dinkin, A. Z. Segal, Y. M. Lee, and J. A. Boockvar

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Flow-based evaluation of cerebral revascularization using near-infrared indocyanine green videoangiography, J. Januszewski, J. S. Beecher, D. J. Chalif, and A. R. Dehdashti

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Central cholinergic activation of a vagus nerve-to-spleen circuit alleviates experimental colitis, H. Ji, M. F. Rabbi, B. Labis, V. A. Pavlov, K. J. Tracey, and J. E. Ghia

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Sequestering HMGB1 via DNA-conjugated beads ameliorates murine colitis, Z. Ju, S. S. Chavan, M. Dancho, T. Tsaava, J. Li, B. Lu, Y. Al-Abed, J. Roth, K. J. Tracey, H. Yang, and +4 additional authors

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Intracellular Hmgb1 inhibits inflammatory nucleosome release and limits acute pancreatitis in mice, R. Kang; Q. Zhang; W. Hou; Z. Yan; R. Chen; J. Bonaroti; P. Bansal; T. R. Billiar; A. Tsung; Q. Wang; D. L. Bartlett; D. C. Whitcomb; E. B. Chang; X. Zhu; H. Wang; B. Lu; K. J. Tracey; L. Cao; X. G. Fan; M. T. Lotze; H. J., 3rd Zeh; and D. Tang

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Hypertensive crisis Reversible edema in leukoencephalopathy, retinopathy, now myelopathy?, G. Kapinos and P. C. Sanelli

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Corticocortical Evoked Potentials Reveal Projectors and Integrators in Human Brain Networks, C. J. Keller, C. J. Honey, L. Entz, S. Bickel, D. M. Groppe, E. Toth, I. Ulbert, F. A. Lado, and A. D. Mehta

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Mapping human brain networks with cortico-cortical evoked potentials, C. J. Keller, C. J. Honey, P. Megevand, L. Entz, I. Ulbert, and A. D. Mehta

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Enhancement of Achilles Tendon Repair Mediated by Matrix Metalloproteinase Inhibition via Systemic Administration of Doxycycline, M. W. Kessler, J. Barr, R. Greenwald, L. B. Lane, J. S. Dines, D. M. Dines, M. C. Drakos, D. A. Grande, and N. O. Chahine

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Middle cerebral artery arrow sign, Z. D. Levy, R. E. Temes, and A. R. Dehdashti

Cardiac resuscitation: current practice and future directions, Z. Levy and T. Slesinger

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Does Intravenous Magnesium Reduce the Need for Hospital Admission Among Adult Patients With Acute Asthma Exacerbations?, Z. Levy and T. L. Slesinger

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Supratentorial cortical ependymoma: Case series and review of the literature, Z. G. Liu, J. Li, Z. Y. Liu, Q. Wang, P. Famer, A. Mehta, D. Chalif, Y. Y. Wang, and J. Y. Li

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JAK/STAT1 signaling promotes HMGB1 hyperacetylation and nuclear translocation, B. Lu, K. Kwan, M. Robinson, M. A. D. Van Zoelen, H. Yang, J. Li, S. S. Chavan, H. Wang, U. Andersson, K. J. Tracey, and +5 additional authors

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Molecular mechanism and therapeutic modulation of high mobility group box 1 release and action: an updated review, B. Lu, C. Wang, M. Wang, W. Li, F. P. Chen, K. J. Tracey, and H. C. Wang

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Inflammation Induces Irreversible Biophysical Changes in Isolated Nucleus Pulposus Cells, R. Maidhof, T. Jacobsen, A. Papatheodorou, and N. O. Chahine

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A distinct vagal anti-inflammatory pathway modulates intestinal muscularis resident macrophages independent of the spleen, G. Matteoli, P. J. Gomez-Pinilla, A. Nemethova, M. Di Giovangiulio, C. Cailotto, S. H. van Bree, K. Michel, K. J. Tracey, P. Vanden Berghe, G. E. Boeckxstaens, and +2 additional authors

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Seeing Scenes: Topographic Visual Hallucinations Evoked by Direct Electrical Stimulation of the Parahippocampal Place Area, P. Megevand, D. M. Groppe, M. S. Goldfinger, S. T. Hwang, P. B. Kingsley, I. Davidesco, and A. D. Mehta

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Semapimod Sensitizes Glioblastoma Tumors to Ionizing Radiation by Targeting Microglia, I. S. Miller, S. Didier, D. W. Murray, T. H. Turner, M. Issaivanan, R. Ruggieri, Y. Al-Abed, and M. Symons

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Central Muscarinic Cholinergic Activation Alters Interaction between Splenic Dendritic Cell and CD4(+)CD25(-) T Cells in Experimental Colitis, P. Munyaka, M. F. Rabbi, V. A. Pavlov, K. J. Tracey, E. Khafipour, and J. E. Ghia

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Guanine nucleotide exchange factor Dock7 mediates HGF- induced glioblastoma cell invasion via Rac activation, D. W. Murray, S. Didier, A. Chan, V. Paulino, L. Van Aelst, R. Ruggieri, N. L. Tran, A. T. Byrne, and M. Symons

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The art of cerebral aneurysms-3 decades of postoperative drawings: review, classification, and efficacy for training, E. Nossek and D. J. Chalif

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O-020 Modifying Flow in the ICA Bifurcation: Pipeline Deployment from the supraclinoid ICA Extending into the M1 Segment: Clinical and Anatomical Results, E. Nossek, D. J. Chalif, S. Chakraborty, and A. Setton

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How I do it: occipital artery to posterior inferior cerebellar artery bypass, E. Nossek, D. J. Chalif, and A. R. Dehdashti

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Modifying flow in the ACA-ACoA complex: endovascular treatment option for wide-neck internal carotid artery bifurcation aneurysms, E. Nossek, D. J. Chalif, M. Levine, and A. Setton

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Internal Maxillary Artery-Middle Cerebral Artery Bypass: Infratemporal Approach for Subcranial-Intracranial (SC-IC) Bypass, E. Nossek, P. Costantino, M. Eisenberg, A. R. Dehdashti, A. Setton, D. J. Chalif, R. A. Ortiz, and D. J. Langer

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Anterior petroclinoid fold fenestration: an adjunct to clipping of postero-laterally projecting posterior communicating aneurysms, E. Nossek, A. Setton, A. R. Dehdashti, and D. J. Chalif

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Consensus on guidelines for stereotactic neurosurgery for psychiatric disorders, B. Nuttin, H. Wu, H. Mayberg, M. Hariz, L. Gabriels, T. Galert, R. Merkel, M. Schulder, Y. J. Li, T. Schlaepfer, and +24 additional authors

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Expanding the borders: the evolution of neurosurgical approaches, M. Ottenhausen, I. Bodhinayake, A. I. Evins, M. Banu, J. A. Boockvar, and A. Bernardo

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VIGAS and beyond: the impact of HCMV-infection and its treatment in glioblastoma, M. Ottenhausen, I. Bodhinayake, P. M. Schaefer, and J. A. Boockvar

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HMGB1 Enhances Immune Suppression by Facilitating the Differentiation and Suppressive Activity of Myeloid-Derived Suppressor Cells, K. H. Parker, P. Sinha, L. A. Horn, V. K. Clements, H. Yang, J. H. Li, K. J. Tracey, and S. Ostrand-Rosenberg

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Multifunctionalization of cetuximab with bioorthogonal chemistries and parallel EGFR profiling of cell-lines using imaging, FACS and immunoprecipitation approaches, M. L. Reschke, R. Uprety, I. Bodhinayake, M. Banu, J. A. Boockvar, and A. A. Sauve

Sudden unexpected nocturnal death in Chiari type 1 malformation and potential role of opioid analgesics, F. Roohi, T. Gropen, and R. W. Kula

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Brain Region-specific Alterations in the Gene Expression of Cytokines, Immune Cell Markers and Cholinergic System Components During Peripheral Endotoxin-induced Inflammation, H. A. Silverman, M. Dancho, A. Regnier-Golanov, M. Nasim, M. Ochani, P. S. Olofsson, M. Ahmed, E. J. Miller, S. S. Chavan, E. Golanov, C. Metz, K. J. Tracey, and V. A. Pavlov

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A Clinical Trial of Progesterone for Severe Traumatic Brain Injury, B. E. Skolnick, A. I. Maas, R. K. Narayan, R. G. van der Hoop, T. MacAllister, J. D. Ward, N. R. Nelson, and N. Stocchetti

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Bacteria and the Neural Code, B. E. Steinberg, K. J. Tracey, and A. S. Slutsky

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Lymphocyte called home: beta2-adreneric neurotransmission confines T cells to lymph nodes to suppress inflammation, K J. Tracey

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Hypertension: An Immune Disorder?, K. J. Tracey

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Approaching the Next Revolution? Evolutionary Integration of Neural and Immune Pathogen Sensing and Response, K. J. Tracey

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Molecular medicine commemorates the career and science of anthony cerami, K. J. Tracey

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High-mobility Group Box 1 Protein Initiates Postoperative Cognitive Decline by Engaging Bone Marrow-derived Macrophages, S. Vacas, V. Degos, K. J. Tracey, and M. Maze

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Phase I/II study of resection and intraoperative cesium-131 radioisotope brachytherapy in patients with newly diagnosed brain metastases., A. G. Wernicke, B. Parashar, D. Nori, K. S. Clifford Chao, P. Christos, I. Kovanlikaya, S. Pannullo, J. A. Boockvar, P. E. Stieg, and T. H. Schwartz

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Cerebral Revascularization for Difficult Skull Base Tumors: A Contemporary Series of 18 Patients, T. Yang, F. Tariq, J. Chabot, R. Madhok, and L. N. Sekhar