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Submissions from 2018

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PDZ-RhoGEF Is a Signaling Effector for TROY-Induced Glioblastoma Cell Invasion and Survival, Z. Ding, H. Dhruv, A. Kwiatkowska-Piwowarczyk, R. Ruggieri, J. Kloss, M. Symons, P. Pirrotte, J. M. Eschbacher, N. L. Tran, and J. C. Loftus

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Successful endoscopic third ventriculostomy in children depends on age and etiology of hydrocephalus: outcome analysis in 51 pediatric patients, S. Duru, J. L. Peiro, M. Oria, E. Aydin, C. Subasi, C. Tuncer, and H. L. Rekate

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Corrigendum to: Image Guidance to Aid Pedicle Screw Fixation of a Lumbar Fracture-Dislocation Injury in a Toddler (vol 105, 1041.e15, 2017), J. K. Houten, J. Nakhla, and S. Ghandi

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Image Guidance to Aid Pedicle Screw Fixation of a Lumbar Fracture-Dislocation Injury in a Toddler (vol 105, 1041.e15, 2017), J. K. Houten, J. Nakhla, and S. Ghandi

Long-term fate of C3-7 arthrodesis: 4-level ACDF versus Cervical Laminectomy and Fusion., J. K. Houten, G. R. Weinstein, and M. Collins

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Expanded Endoscopic Transsphenoidal Resection of Tuberculum Sella Meningioma Invading the Optic Canal, G. Klironomos, M. Bruni, and A. R. Dehdashti

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Congenital cervical kyphosis in an infant with Ehlers-Danlos syndrome, A. J. Kobets, D. Komlos, and J. K. Houten

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Intracranial electrophysiology reveals reproducible intrinsic functional connectivity within human brain networks, A. Kucyi, J. Schrouff, S. Bickel, B. L. Foster, J. M. Shine, and J. Parvizi

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Nimodipine for the treatment of otolaryngic indications, Z. D. Levy, H. Shafeeq, and J. H. Sin

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Correction: First results on survival from a large Phase 3 clinical trial of an autologous dendritic cell vaccine in newly diagnosed glioblastoma [J Transl Med., 16, (2018) (142)] DOI: 10.1186/s12967-018-1507-6, L. M. Liau, K. Ashkan, D. D. Tran, J. L. Campian, J. E. Trusheim, C. S. Cobbs, J. A. Heth, M. Salacz, M. Schulder, M. L. Bosch, and +10 additional authors

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Correction to: First results on survival from a large Phase 3 clinical trial of an autologous dendritic cell vaccine in newly diagnosed glioblastoma, L. M. Liau, K. Ashkan, D. D. Tran, J. L. Campian, J. E. Trusheim, C. S. Cobbs, J. A. Heth, M. Salacz, M. Schulder, M. L. Bosch, and +59 additional authors

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First results on survival from a large Phase 3 clinical trial of an autologous dendritic cell vaccine in newly diagnosed glioblastoma, L. M. Liau, K. Ashkan, D. D. Tran, J. L. Campian, J. E. Trusheim, C. S. Cobbs, J. A. Heth, M. Salacz, M. Schulder, M. L. Bosch, and +59 additional authors

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Safety and Efficacy of a 3-Dimensional Stent Retriever With Aspiration-Based Thrombectomy vs Aspiration-Based Thrombectomy Alone in Acute Ischemic Stroke Intervention A Randomized Clinical Trial, R. G. Nogueira, D. Frei, J. F. Kirmani, O. Zaidat, D. Lopes, A. S. Turk, D. Heck, B. Mason, D. Langer, A. Siddiqui, and +9 additional authors

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Internal Maxillary Artery to Middle Cerebral Artery Cranial Bypass: The New “Work Horse” for Cerebral Flow Replacement, E. Nossek and D. J. Langer

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Trapping and resection of cortical MCA mycotic aneurysm in eloquent area, E. Nossek, A. Setton, and D. J. Chalif

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Do craniopharyngioma molecular signatures correlate with clinical characteristics?, S. B. Omay, Y. N. Chen, J. P. Almeida, A. S. Ruiz-Trevino, J. A. Boockvar, P. E. Stieg, J. P. Greenfield, M. M. Souweidane, A. Kacker, T. H. Schwartz, and +2 additional authors

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On the importance of precise electrode placement for targeted transcranial electric stimulation, A. Opitz, E. Yeagle, A. Thielscher, C. Schroeder, A. D. Mehta, and M. P. Milham

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Intradural spinal tumors in adults—update on management and outcome, M. Ottenhausen, G. Ntoulias, I. Bodhinayake, F. H. Ruppert, S. Schreiber, A. Förschler, J. A. Boockvar, and A. Jödicke

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Joint Representation of Spatial and Phonetic Features in the Human Core Auditory Cortex, P. Patel, L. K. Long, J. L. Herrero, A. D. Mehta, and N. Mesgarani

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Molecular and Functional Neuroscience in Immunity, V. A. Pavlov, S. S. Chavan, and K. J. Tracey

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Re: Editorial by Professors Brodbelt and Flint, H. L. Rekate

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Minimally Invasive Alternative Approaches to Pterional Craniotomy: A Systematic Review of the Literature, J. Rychen, D. Croci, M. Roethlisberger, E. Nossek, M. Potts, I. Radovanovic, H. Riina, L. Mariani, R. Guzman, and D. W. Zumofen

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Medial prefrontal cortex supports perceptual memory, C. M. Schwiedrzik, S. S. Sudmann, T. Thesen, X. Wang, D. M. Groppe, P. Megevand, W. Doyle, A. D. Mehta, O. Devinsky, and L. Melloni

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Elaborate mapping of the posterior visual pathway in awake craniotomy, T. Shahar, A. Korn, G. Barkay, T. Biron, A. Hadanny, T. Gazit, E. Nossek, M. Ekstein, A. Kesler, and Z. Ram

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Dynamic Hydrostatic Pressure Regulates Nucleus Pulposus Phenotypic Expression and Metabolism in a Cell Density-Dependent Manner, B. S. Shah and N. O. Chahine

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Aerobic Exercise Training and Inducible Inflammation: Results of a Randomized Controlled Trial in Healthy, Young Adults., R. P. Sloan, P. A. Shapiro, P. S. McKinley, M. Bartels, D. Shimbo, V. Lauriola, W. Karmally, M. Pavlicova, C. J. Choi, K. J. Tracey, and +3 additional authors

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The lymphocyte-to-monocyte ratio as a prognostic indicator in head and neck cancer: a systematic review and meta-analysis, T. Tham, C. Olson, J. Khaymovich, S. W. Herman, and P. D. Costantino

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Evaluation of the prognostic utility of the hemoglobin-to-red cell distribution width ratio in head and neck cancer, T. Tham, C. Olson, M. Wotman, S. Teegala, J. Khaymovich, J. Coury, and P. Costantino

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Efficacy of a non-invasive middle ear aeration device in children with recurrent otitis media: A randomized controlled trial protocol, T. Tham, L. Rahman, and P. Costantino

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Venous Thromboembolism Risk in Head and Neck Cancer: Significance of the Preoperative Platelet-to-Lymphocyte Ratio, T. Tham, L. Rahman, C. Persaud, C. Olson, and P. Costantino

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Neurons Are the Inflammatory Problem, K. J. Tracey

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An Unusual Presentation of Chronic Subdural Hematoma with Isolated Footdrop., S. D. Weisberg and J. K. Houten

Submissions from 2017

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Colony Stimulating Factor-1 Receptor Inhibitors-A 4 for 1 Deal in the Desire to Improve Glioma Radiotherapy, B. Skeie, R. Ruggieri, J. A. Boockvar, and M. Symons

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Hippocampal-sparing and target volume coverage in treating 3 to 10 brain metastases: A comparison of Gamma Knife, single-isocenter VMAT, CyberKnife, and TomoTherapy stereotactic radiosurgery., I. Zhang, J. Antone, J. Li, S. Saha, A. C. Riegel, L. Vijeh, J. Lauritano, M. Marrero, S. Salas, M. Schulder, H. Zinkin, A. Goenka, and J. Knisely

Submissions from 2016

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To the editor: Radiation plus Chemotherapy in Low-Grade Glioma, J. Knisely and M. Schulder

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Curcumin changes the polarity of tumor-associated microglia and eliminates glioblastoma, S. Mukherjee, J. Baidoo, A. Fried, D. Atwi, S. Dolai, J. Boockvar, M. Symons, R. Ruggieri, K. Raja, and P. Banerjee

Outcomes in Patients with Vestibular Schwannoma after Subtotal Resection and Adjuvant Radiosurgery, H. Radwan, M. Bruce Eisenberg, J. P. S. Knisely, M. M. Ghaly, and M. Schulder

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Neurosurgeons' Critical Role in Managing Traumatic Brain Injury, J. S. Ullman, S. D. Timmons, and A. B. Valadka

Submissions from 2015

Synaptojanin 2 is a druggable mediator of metastasis and the gene is overexpressed and amplified in breast cancer, N. Ben-Chetrit, D. Chetrit, A. Abdul-Hai, T. Itkin, S. Carvalho, H. Cohen-Dvashi, W. J. Koestler, M. Symons, M. Ehrlich, Y. Yarden, and +21 additional authors

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Comparison of indocyanine green fluorescent angiography to digital subtraction angiography in brain arteriovenous malformation surgery, C. J. Bilbao, T. Bhalla, S. Dalal, H. Patel, and A. R. Dehdashti

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Prolonged mechanical ventilation is associated with pulmonary complications, increased length of stay, and unfavorable discharge destination among patients with subdural hematoma, K. M. Busl, B. Ouyang, T. A. Boland, S. Pollandt, and R. E. Temes

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Sepsis: a roadmap for future research, J. Cohen, J. L. Vincent, N. K. Adhikari, F. R. Machado, S. Giulieri, J. Delaloye, S. Opal, K. Tracey, T. van der Poll, E. Pelfrene, and +3 additional authors

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Ophthalmic artery aneurysm treated by surgical clipping and balloon-assisted temporary carotid occlusion, A. R. Dehdashti

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Surgical treatment of a large ruptured internal carotid artery bifurcation aneurysm, A. R. Dehdashti

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The suboccipital midline approach to foramen magnum meningiomas; feasible, but is it optimal?, A. R. Dehdashti

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First-In-Human, Phase 1, Randomized, Dose-Escalation Trial with Recombinant Anti-IL-20 Monoclonal Antibody in Patients with Psoriasis, A. B. Gottlieb, J. G. Krueger, M. Sandberg Lundblad, M. Gothberg, and B. E. Skolnick

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Tight regulation between cell survival and programmed cell death in GBM stem-like cells by EGFR/GSK3b/PP2A signaling, D. B. Gursel, M. A. Banu, N. Berry, R. Marongiu, J. K. Burkhardt, K. Kobylarz, M. G. Kaplitt, S. Rafii, and J. A. Boockvar

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Laminar Profile and Physiology of the alpha Rhythm in Primary Visual, Auditory, and Somatosensory Regions of Neocortex, S. Haegens, A. Barczak, G. Musacchia, M. L. Lipton, A. D. Mehta, P. Lakatos, and C. E. Schroeder

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Notch receptor expression in human brain arteriovenous malformations, S. Hill-Felberg, H. H. Wu, S. A. Toms, and A. R. Dehdashti

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The Comparative Effectiveness of Specific Professional Educational Tools for Correcting Knowledge Gaps Among Practicing Neurosurgeons, B. L. Hoh, J. Curran, J. Rokicki, J. S. Ullman, B. R. Bendok, G. Rao, N. R. Selden, D. K. Resnick, and Z. Ghogawala

Redefining secondary injury after subarachnoid hemorrhage in light of multimodal advanced neuroimaging, intracranial and transcranial neuromonitoring: beyond vasospasm, G. Kapinos

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Forearm Cephalic Vein Graft for Short, "Middle"-Flow, Internal Maxillary Artery to Middle Cerebral Artery Bypass, E. Nossek, P. Costantino, D. J. Chalif, R. A. Ortiz, A. R. Dehdashti, and D. J. Langer

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Recidivism among ED super users after implementation of a pain protocol, B. Passarello, Z. Levy, B. Levine, M. Papas, and N. Jasani

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Neural circuitry and immunity, V. Pavlov and K. J. Tracey

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Finally, open loop control of intracranial pressure in hydrocephalus, H. L. Rekate

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Lumboatrial shunt in a patient with Crouzon syndrome complicated by pseudotumor cerebri, E. W. Sankey, M. H. Khattab, B. D. Elder, C. R. Goodwin, H. L. Rekate, and D. Rigamonti

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Progesterone in Traumatic Brain Injury REPLY, B. E. Skolnick, A. I. R. Maas, and R. K. Narayan

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Approaching the Next Revolution? Evolutionary Integration of Neural and Immune Pathogen Sensing and Response, K. J. Tracey

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SHOCK MEDICINE, K. J. Tracey

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Accuracy of the ABC/2 Score for Intracerebral Hemorrhage: Systematic Review and Analysis of MISTIE, CLEAR-IVH, and CLEAR III, A. J. Webb, N. L. Ullman, T. C. Morgan, J. Muschelli, J. Kornbluth, I. A. Awad, S. Mayo, M. Rosenblum, R. Narayan, D. F. Hanley, and +14 additional authors

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Stress Induces the Danger-Associated Molecular Pattern HMGB-1 in the Hippocampus of Male Sprague Dawley Rats: A Priming Stimulus of Microglia and the NLRP3 Inflammasome, M. D. Weber, M. G. Frank, K. J. Tracey, L. R. Watkins, and S. F. Maier

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HbSC Disease and Spontaneous Epidural Hematoma with Kernohan's Notch Phenomena, M. Yogarajah, C. C. Agu, B. Sivasambu, and M. A. Mittler

Submissions from 2014

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The functions of HMGB1 depend on molecular localization and post-translational modifications Introduction, U. Andersson, D. J. Antoine, and K. J. Tracey

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A Systematic Nomenclature for the Redox States of High Mobility Group Box (HMGB) Proteins, D. J. Antoine, H. E. Harris, U. Andersson, K. J. Tracey, and M. E. Bianchi

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Targeting a heterogeneous tumor: the promise of the interleukin-13 receptor alpha2, I. Bodhinayake, M. Ottenhausen, and J. A. Boockvar

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Results and risk factors for recurrence following endoscopic endonasal transsphenoidal surgery for pituitary adenoma, I. Bodhinayake, M. Ottenhausen, M. A. Mooney, K. Kesavabhotla, P. Christos, J. T. Schwarz, and J. A. Boockvar

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Farewell Statement from Dr. Cerami and Dr. Tracey as Outgoing Co-Editors in Chief of Molecular Medicine, A. Cerami and K. J. Tracey

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Nanocomposite Scaffold for Chondrocyte Growth and Cartilage Tissue Engineering: Effects of Carbon Nanotube Surface Functionalization, N. O. Chahine, N. M. Collette, C. B. Thomas, D. C. Genetos, and G. G. Loots

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Novel hydrogel application in minimally invasive surgical approaches to spontaneous intracranial hypotension. Report of 2 cases, C. M. Chai, M. A. Banu, W. Cobb, N. Mehta, L. Heier, and J. A. Boockvar

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Regulating innate immunity with dopamine and electroacupuncture, S. S. Chavan and K. J. Tracey

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Sepsis: Current Dogma and New Perspectives, C. S. Deutschman and K. J. Tracey

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Prophylactic plastic surgery closure of neurosurgical scalp incisions reduces the incidence of wound complications in previously-operated patients treated with bevacizumab (Avastin(R)) and radiation, A. R. Golas, T. Boyko, T. H. Schwartz, P. E. Stieg, J. A. Boockvar, and J. A. Spector

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Conservative management of cavernous sinus cavernous hemangioma in pregnancy, J. S. Haber, K. Kesavabhotla, M. Ottenhausen, I. Bodhinayake, M. J. Dinkin, A. Z. Segal, Y. M. Lee, and J. A. Boockvar

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Central cholinergic activation of a vagus nerve-to-spleen circuit alleviates experimental colitis, H. Ji, M. F. Rabbi, B. Labis, V. A. Pavlov, K. J. Tracey, and J. E. Ghia

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Hypertensive crisis Reversible edema in leukoencephalopathy, retinopathy, now myelopathy?, G. Kapinos and P. C. Sanelli

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Mapping human brain networks with cortico-cortical evoked potentials, C. J. Keller, C. J. Honey, P. Megevand, L. Entz, I. Ulbert, and A. D. Mehta

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Middle cerebral artery arrow sign, Z. D. Levy, R. E. Temes, and A. R. Dehdashti

Cardiac resuscitation: current practice and future directions, Z. Levy and T. Slesinger

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Does Intravenous Magnesium Reduce the Need for Hospital Admission Among Adult Patients With Acute Asthma Exacerbations?, Z. Levy and T. L. Slesinger

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Supratentorial cortical ependymoma: Case series and review of the literature, Z. G. Liu, J. Li, Z. Y. Liu, Q. Wang, P. Famer, A. Mehta, D. Chalif, Y. Y. Wang, and J. Y. Li

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A distinct vagal anti-inflammatory pathway modulates intestinal muscularis resident macrophages independent of the spleen, G. Matteoli, P. J. Gomez-Pinilla, A. Nemethova, M. Di Giovangiulio, C. Cailotto, S. H. van Bree, K. Michel, K. J. Tracey, P. Vanden Berghe, G. E. Boeckxstaens, and +2 additional authors

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Central Muscarinic Cholinergic Activation Alters Interaction between Splenic Dendritic Cell and CD4(+)CD25(-) T Cells in Experimental Colitis, P. Munyaka, M. F. Rabbi, V. A. Pavlov, K. J. Tracey, E. Khafipour, and J. E. Ghia

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The art of cerebral aneurysms-3 decades of postoperative drawings: review, classification, and efficacy for training, E. Nossek and D. J. Chalif

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How I do it: occipital artery to posterior inferior cerebellar artery bypass, E. Nossek, D. J. Chalif, and A. R. Dehdashti

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Modifying flow in the ACA-ACoA complex: endovascular treatment option for wide-neck internal carotid artery bifurcation aneurysms, E. Nossek, D. J. Chalif, M. Levine, and A. Setton

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Anterior petroclinoid fold fenestration: an adjunct to clipping of postero-laterally projecting posterior communicating aneurysms, E. Nossek, A. Setton, A. R. Dehdashti, and D. J. Chalif

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Consensus on guidelines for stereotactic neurosurgery for psychiatric disorders, B. Nuttin, H. Wu, H. Mayberg, M. Hariz, L. Gabriels, T. Galert, R. Merkel, M. Schulder, Y. J. Li, T. Schlaepfer, and +24 additional authors

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Expanding the borders: the evolution of neurosurgical approaches, M. Ottenhausen, I. Bodhinayake, A. I. Evins, M. Banu, J. A. Boockvar, and A. Bernardo

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VIGAS and beyond: the impact of HCMV-infection and its treatment in glioblastoma, M. Ottenhausen, I. Bodhinayake, P. M. Schaefer, and J. A. Boockvar

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Multifunctionalization of cetuximab with bioorthogonal chemistries and parallel EGFR profiling of cell-lines using imaging, FACS and immunoprecipitation approaches, M. L. Reschke, R. Uprety, I. Bodhinayake, M. Banu, J. A. Boockvar, and A. A. Sauve

Sudden unexpected nocturnal death in Chiari type 1 malformation and potential role of opioid analgesics, F. Roohi, T. Gropen, and R. W. Kula

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A Clinical Trial of Progesterone for Severe Traumatic Brain Injury, B. E. Skolnick, A. I. Maas, R. K. Narayan, R. G. van der Hoop, T. MacAllister, J. D. Ward, N. R. Nelson, and N. Stocchetti

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Bacteria and the Neural Code, B. E. Steinberg, K. J. Tracey, and A. S. Slutsky

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Lymphocyte called home: beta2-adreneric neurotransmission confines T cells to lymph nodes to suppress inflammation, K J. Tracey

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Hypertension: An Immune Disorder?, K. J. Tracey

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Approaching the Next Revolution? Evolutionary Integration of Neural and Immune Pathogen Sensing and Response, K. J. Tracey

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Molecular medicine commemorates the career and science of anthony cerami, K. J. Tracey

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High-mobility Group Box 1 Protein Initiates Postoperative Cognitive Decline by Engaging Bone Marrow-derived Macrophages, S. Vacas, V. Degos, K. J. Tracey, and M. Maze

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Phase I/II study of resection and intraoperative cesium-131 radioisotope brachytherapy in patients with newly diagnosed brain metastases., A. G. Wernicke, B. Parashar, D. Nori, K. S. Clifford Chao, P. Christos, I. Kovanlikaya, S. Pannullo, J. A. Boockvar, P. E. Stieg, and T. H. Schwartz