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Submissions from 2014

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Use of PER977 to Reverse the Anticoagulant Effect of Edoxaban, J. E. Ansell, S. H. Bakhru, B. E. Laulicht, S. S. Steiner, M. Grosso, K. Brown, V. Dishy, R. J. Noveck, and J. C. Costin

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Medical orders for life-sustaining treatment: Is it time yet?, A. C. Araw, A. M. Araw, R. Pekmezaris, C. N. Nouryan, C. Sison, B. Tommasulo, and G. P. Wolf-Klein

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Treatment of lupus nephritis with abatacept: the Abatacept and Cyclophosphamide Combination Efficacy and Safety Study, A. Askanase, M. Byron, L. Keyes-Elstein, P. Cagnoli, J. McCune, B. Diamond, D. Daikh, A. Davidson, M. Mackay, D. Wofsy, and +24 additional authors

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Lymphoma risk in systemic lupus: effects of disease activity versus treatment, S. Bernatsky, R. Ramsey-Goldman, L. Joseph, J. F. Boivin, K. H. Costenbader, M. B. Urowitz, D. D. Gladman, P. R. Fortin, C. Aranow, A. E. Clarke, and +27 additional authors

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Identification of Stage-Specific Genes Associated With Lupus Nephritis and Response to Remission Induction in (NZB x NZW)F1 and NZM2410 Mice, R. Bethunaickan, C. C. Berthier, W. J. Zhang, R. Eksi, H. D. Li, Y. F. Guan, M. Kretzler, and A. Davidson

Coverage Isn't Enough: Building Primary Care Capacity in the Setting of Health Reform, L. Block, B. G. Cook, L. A. Hanyok, D. de la Torre, M. M. Rogers, G. Noronha, and M. Sylvia

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A post-2011 time motion study--the authors' reply, L. Block, R. Habicht, A. W. Wu, S. V. Desai, K. Wang, K. N. Silva, T. Niessen, N. Oliver, and L. Feldman

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Inpatient safety outcomes following the 2011 residency work-hour reform, L. Block, M. Jarlenski, A. W. Wu, L. Feldman, J. Conigliaro, J. Swann, and S. V. Desai

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We Could Have Done a Better Job: A Qualitative Study of Medical Student Reflections on Safe Hospital Discharge, L. Block, M. Morgan-Gouveia, R. B. Levine, and D. Cayea

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Barriers and Facilitators of Implementation of a Mandate for Influenza Vaccination among Healthcare Personnel, L. Block, S. Pitts, and T. M. Perl

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MIF: Mood Improving/Inhibiting Factor?, J. Bloom and Y. Al-Abed

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The gut microbiota influences blood-brain barrier permeability in mice, V. Braniste, M. Al-Asmakh, C. Kowal, F. Anuar, A. Abbaspour, M. Toth, A. Korecka, B. T. Volpe, B. Diamond, S. Pettersson, and +8 additional authors

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Factors associated with damage accrual in patients with systemic lupus erythematosus: results from the Systemic Lupus International Collaborating Clinics (SLICC) Inception Cohort, I. N. Bruce, A. G. O'Keeffe, V. Farewell, J. G. Hanly, S. Manzi, L. Su, D. D. Gladman, S. C. Bae, C. Aranow, M. B. Urowitz, and +30 additional authors

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Curricular Content of Internal Medicine Residency Programs: A Nationwide Report, S. I. Chaudhry, C. Lien, J. Ehrlich, S. Lane, K. Cordasco, F. S. McDonald, V. M. Arora, and A. Steinmann

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Murine Genetically Engineered and Human Xenograft Models of Chronic Lymphocytic Leukemia, S. S. Chen and N. Chiorazzi

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D-dimer and risk of thromboembolic and bleeding events in patients with atrial fibrillation - observations from the ARISTOTLE trial, C. Christersson, L. Wallentin, U. Andersson, J. H. Alexander, J. Ansell, R. De Caterina, B. J. Gersh, C. B. Granger, M. Hanna, A. Siegbahn, and +5 additional authors

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D-dimer as a predictor of venous thromboembolism in acutely ill, hospitalized patients: a subanalysis of the randomized controlled MAGELLAN trial, A. T. Cohen, T. E. Spiro, A. C. Spyropoulos, Y. H. Desanctis, M. Homering, H. R. Buller, L. Haskell, D. Hu, R. Hull, P. Burton, and +4 additional authors

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Reversal Agents in Development for the New Oral Anticoagulants, J. Costin, J. Ansell, B. Laulicht, S. Bakhru, and S. Steiner

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The influence of polygenic risk scores on heritability of anti-CCP level in RA, J. Cui, K. E. Taylor, Y. C. Lee, H. Kallberg, M. E. Weinblatt, J. S. Coblyn, L. Klareskog, L. A. Criswell, P. K. Gregersen, E. W. Karlson, and +2 additional authors

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Interferon alpha on NZM2328.Lc1R27: Enhancing autoimmunity and immune complex-mediated glomerulonephritis without end stage renal failure, C. Dai, H. Y. Wang, S. S. J. Sung, R. Sharma, C. Kannapell, W. Han, Q. Wang, A. Davidson, F. Gaskin, and S. M. Fu

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Autoimmunity to Vimentin and Lupus Nephritis, A. Davidson

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Smoking as a risk factor for the radiological severity of rheumatoid arthritis: a study on six cohorts, D. P. C. de Rooy, J. A. B. van Nies, M. C. Kapetanovic, H. Kristjansdottir, M. L. E. Andersson, K. Forslind, Dmfm van der Heijde, P. K. Gregersen, E. Lindqvist, A. H. M. van der Helm-van Mil, and +3 additional authors

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A genetic variant in the region of MMP-9 is associated with serum levels and progression of joint damage in rheumatoid arthritis, D. P. C. de Rooy, A. Zhernakova, R. Tsonaka, A. Willemze, B. A. S. Kurreeman, G. Trynka, L. van Toorn, R. E. M. Toes, P. K. Gregersen, A. H. M. van der Helm-van Mil, and +2 additional authors

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STABLE Results: Warfarin Home Monitoring Achieves Excellent INR Control, G. De Santis, J. Hogan-Schlientz, G. Liska, S. Kipp, R. Sallee, M. Wurster, K. Kupfer, and J. Ansell

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Letter from Incoming Editor in Chief of Molecular Medicine, Dr. Betty Diamond, B. Diamond

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Clinical Implications of the Obese-Asthma Phenotypes, J. Diaz and S. Farzan

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National Assessment of Warfarin Anticoagulation Therapy for Stroke Prevention in Atrial Fibrillation, J. S. Dlott, R. A. George, X. H. Huang, M. Odeh, H. W. Kaufman, J. Ansell, and E. M. Hylek

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Approaches to achieving equality in respiratory health, P. W. Finn and R. Cohen

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Impact on house staff evaluation scores when changing from a Dreyfus- to a Milestone-based evaluation model: one internal medicine residency program's findings, K. A. Friedman, S. Balwan, F. Cacace, K. Katona, S. Sunday, and S. Chaudhry

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Lloyd Mayer, MD, 1952-2013, In Memoriam, S. M. Fu, C. Cunningham-Rundles, B. Diamond, D. Rotrosen, W. Stohl, and C. Terhorst

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Circulating complexes of the vitamin D binding protein with G-actin induce lung inflammation by targeting endothelial cells, L. Y. Ge, G. Trujillo, E. J. Miller, and R. R. Kew

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Immunochip Identifies Novel, and Replicates Known, Genetic Risk Loci for Rheumatoid Arthritis in Black South Africans, N. Govind, A. Choudhury, B. Hodkinson, C. Ickinger, J. Frost, A. Lee, P. K. Gregersen, R. J. Reynolds, S. L. Bridges, M. Tikly, and +2 additional authors

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Genetics. A genomic road map for complex human disease, P. K. Gregersen

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The Power of a Modular Approach to Transcriptional Analysis, P. K. Gregersen and M. Oswald

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Underrecognition of Osteoporosis in Men in the Long-Term Care Setting, A. Gupta, R. Pekmezaris, A. Kozikowski, N. Kohn, and G. Wolf-Klein

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Fine mapping seronegative and seropositive rheumatoid arthritis to shared and distinct HLA alleles by adjusting for the effects of heterogeneity, B. Han, D. Diogo, S. Eyre, H. Kallberg, A. Zhernakova, J. Bowes, L. Padyukov, Y. Okada, P. K. Gregersen, S. Raychaudhuri, and +8 additional authors

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Effects of prostaglandin E-2 on p53 mRNA transcription and p53 mutagenesis during T-cell-independent human B-cell clonal expansion, S. Haque, X. J. Yan, L. Rosen, S. McCormick, N. Chiorazzi, and P. K. A. Mongini

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Clinical outcomes and management associated with major bleeding in patients with atrial fibrillation treated with apixaban or warfarin: insights from the ARISTOTLE trial, C. Held, E. M. Hylek, J. H. Alexander, M. Hanna, R. D. Lopes, D. M. Wojdyla, L. Thomas, H. Al-Khalidi, J. Ansell, L. Wallentin, and +8 additional authors

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Novel Arylazoarylmethane as Potential Inhibitor of Macrophage Migration Inhibitory Factor, M. Z. He, C. Metz, K. F. Cheng, J. Ling, T. Coleman, S. VanPatten, and Y. Al-Abed

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B-1a Cell Diversity: Nontemplated Addition in B-1a Cell Ig Is Determined by Progenitor Population and Developmental Location, N. E. Holodick, T. Vizconde, and T. L. Rothstein

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Splenic B-1a Cells Expressing CD138 Spontaneously Secrete Large Amounts of Immunoglobulin in Naive Mice, N. E. Holodick, T. Vizconde, and T. L. Rothstein

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Genomic imbalance defines three prognostic groups for risk stratification of patients with chronic lymphocytic leukemia, J. Houldsworth, A. Guttapalli, V. Thodima, X. J. Yan, G. Mendiratta, T. Zielonka, G. Nanjangud, K. Rai, N. Chiorazzi, R. S. K. Chaganti, and +4 additional authors

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Safely expanding the donor pool: brain dead donors with history of temporary cardiac arrest, D. P. Hoyer, A. Paul, F. Saner, A. Gallinat, Z. Mathe, M. Schulze, G. M. Kaiser, A. Canbay, E. Molmenti, G. C. Sotiropoulos, and +1 additional author

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IGHV1-69 B Cell Chronic Lymphocytic Leukemia Antibodies Cross-React with HIV-1 and Hepatitis C Virus Antigens as Well as Intestinal Commensal Bacteria, K. K. Hwang, A. M. Trama, D. M. Kozink, S. L. Allen, K. R. Rai, R. Catera, X. J. Yan, C. C. Chu, N. Chiorazzi, B. F. Haynes, and +12 additional authors

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Sudden unexpected death in schizophrenia: Autopsy findings in psychiatric inpatients, P. Ifteni, C. U. Correll, V. Burtea, J. M. Kane, and P. Manu

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Rapid clozapine titration in treatment-refractory bipolar disorder, P. Ifteni, C. U. Correll, J. Nielsen, V. Burtea, J. M. Kane, and P. Manu

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Effectiveness and safety of rapid clozapine titration in schizophrenia, P. Ifteni, J. Nielsen, V. Burtea, C. U. Correll, J. M. Kane, and P. Manu

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ISO-66, a novel inhibitor of macrophage migration inhibitory factor, shows efficacy in melanoma and colon cancer models, K. Ioannou, K. F. Cheng, G. V. Crichlow, A. I. Birmpilis, E. J. Lolis, O. E. Tsitsilonis, and Y. Al-Abed

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Genotyping of immune-related genetic variants identifies TYK2 as a novel associated locus for idiopathic inflammatory myopathies, M. Jani, J. Massey, L. R. Wedderburn, J. Vencovsky, K. Danko, I. E. Lundberg, L. Padyukov, A. Lee, P. K. Gregersen, Eumyonet, and +10 additional authors

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Are Nurses an Answer to New Primary Care Needs?, S. Jauhar and D. Battinelli

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Hormonal milieu at time of B cell activation controls duration of autoantibody response, V. Jeganathan, E. Peeva, and B. Diamond

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Glomerular Diseases Associated With Cancer, Chemotherapy, and Hematopoietic Stem Cell Transplantation, K. D. Jhaveri, H. H. Shah, C. Patel, A. Kadiyala, M. B. Stokes, and J. Radhakrishnan

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Sequestering HMGB1 via DNA-conjugated beads ameliorates murine colitis, Z. Ju, S. S. Chavan, M. Dancho, T. Tsaava, J. Li, B. Lu, Y. Al-Abed, J. Roth, K. J. Tracey, H. Yang, and +4 additional authors

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A Novel Mechanism of B Cell-Mediated Immune Suppression through CD73 Expression and Adenosine Production, H. Kaku, K. F. Cheng, Y. Al-Abed, and T. L. Rothstein

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Inhibition of Cxcr 1 and 2 Delays Preterm Delivery and Reduces Neonatal Mortality in a Mouse Model of Chorioamnionitis, R. Kamity, H. Patel, S. Younis, M. Nasim, E. Miller, and M. Ahmed

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Steroid use in acute liver failure, J. Karkhanis; E. C. Verna; M. S. Chang; R. T. Stravitz; M. Schilsky; W. M. Lee; and R. S., Jr. Brown

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Reply: To PMID 23929808, J. Karkhanis; E. C. Verna; M. S. Chang; R. T. Stravitz; M. L. Schilsky; W. M. Lee; and R. S., Jr. Brown

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Modulation of tolerogenic dendritic cells and autoimmunity, S. J. Kim and B. Diamond

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Expression of Blimp-1 in dendritic cells modulates the innate inflammatory response in dextran sodium sulfate-induced colitis, S. J. Kim, J. Goldstein, K. Dorso, M. Merad, L. Mayer, J. M. Crawford, P. K. Gregersen, and B. Diamond

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Identification of a genetic variant for joint damage progression in autoantibody-positive rheumatoid arthritis, R. Knevel, K. Klein, K. Somers, C. Ospelt, J. J. Houwing-Duistermaat, M. Kern, N. Manjarrez-Orduno, L. Rodriguez-Rodriquez, P. K. Gregersen, A. H. van der Helm-van Mil, and +13 additional authors

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2014 ESC guidelines on the diagnosis and management of acute pulmonary embolism, S. V. Konstantinides, A. Torbicki, G. Agnelli, N. Danchin, D. Fitzmaurice, N. Galie, J. S. Gibbs, A. C. Spyropoulos, M. V. Huisman, M. Zompatori, and +15 additional authors

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Potential Costs of Inappropriate Use of Proton Pump Inhibitors, A. M. Ladd, G. Panagopoulos, J. Cohen, N. Mar, and R. Graham

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Genome-Wide Methylation Analyses in Glioblastoma Multiforme, R. K. Lai, Y. W. Chen, X. W. Guan, D. Nousome, C. Sharma, P. Canoll, J. Bruce, A. Lee, P. Gregersen, J. Barnholtz-Sloan, and +8 additional authors

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Angiopoietin-2: A Key to Understanding Sepsis and Its Pulmonary Sequelae?, J. Y. Lee and E. J. Miller

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25-Hydroxyvitamin D and Cardiovascular Disease in Patients With Systemic Lupus Erythematosus: Data From a Large International Inception Cohort, A. Lertratanakul, P. Wu, A. Dyer, M. Urowitz, D. Gladman, C. Aranow, J. Font, R. van Vollenhoven, T. Stoll, R. Ramsey-Goldman, and +20 additional authors

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Direct Oral Anticoagulants New Drugs and New Concepts, J. H. Levy, A. C. Spyropoulos, C. M. Samama, and J. Douketis

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Relationship Between Alcohol Use Categories and Noninvasive Markers of Advanced Hepatic Fibrosis in HIV-Infected, Chronic Hepatitis C Virus-Infected, and Uninfected Patients, J. K. Lim, J. P. Tate, S. L. Fultz, J. L. Goulet, J. Conigliaro, K. J. Bryant, A. J. Gordon, C. Gibert, D. Rimland, V. Lo Re, and +4 additional authors

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NF-kappa B-to-AP-1 Switch: A Mechanism Regulating Transition From Endothelial Barrier Injury to Repair in Endotoxemic Mice, G. Liu, X. B. Ye, E. J. Miller, and S. F. Liu

External validation of a risk assessment model for venous thromboembolism in the hospitalised acutely-ill medical patient (VTE-VALOURR), C. E. Mahan, Y. Liu, A. G. Turpie, J. T. Vu, N. Heddle, R. J. Cook, U. Dairkee, and A. C. Spyropoulos

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Measures of User experience in a Streptococcal pharyngitis and Pneumonia Clinical Decision Support Tools, D. Mann, M. Knaus, L. McCullagh, A. Sofianou, L. Rosen, T. McGinn, and J. Kannry

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Acanthosis Nigricans During Treatment With Aripiprazole, P. Manu, Z. Al-Dhaher, N. Dargani, and C. U. Correll

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Elevated Blood Urea Nitrogen and Medical Outcome of Psychiatric Inpatients, P. Manu, Z. Al-Dhaher, S. Khan, J. M. Kane, and C. U. Correll

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Markers of inflammation in schizophrenia: association vs. causation, P. Manu, C. U. Correll, M. Wampers, A. J. Mitchell, M. Probst, D. Vancampfort, and M. De Hert

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Dysmetabolic features of the overweight patients receiving antipsychotic drugs: A comparison with normal weight and obese subjects, P. Manu, C. U. Correll, M. Wampers, R. van Winkel, W. Yu, D. Shiffeldrim, and M. De Hert

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Body Mass Index Identified as an Independent Predictor of Psychiatric Readmission, P. Manu, S. Khan, R. Radhakrishnan, M. J. Russ, J. M. Kane, and C. U. Correll

Efficacy and safety of early parenteral anticoagulation as a bridge to warfarin after mechanical valve replacement, J. G. Mathew, A. C. Spyropoulos, A. Yusuf, J. Vincent, J. Eikelboom, O. Shestakovska, S. Fremes, J. Noora, L. R. Guo, R. Whitlock, and +2 additional authors

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Immunochip Analysis Identifies Multiple Susceptibility Loci for Systemic Sclerosis, M. D. Mayes, L. Bossini-Castillo, O. Gorlova, J. E. Martin, X. D. Zhou, W. V. Chen, S. Assassi, P. K. Gregersen, A. T. Lee, J. Martin, and +66 additional authors

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User Centered Clinical Decision Support Tools: Adoption across Clinician Training Level, L. J. McCullagh, A. Sofianou, J. Kannry, D. M. Mann, and T. G. McGinn

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Longitudinal adoption rates of complex decision support tools in primary care, L. McCullagh, D. Mann, L. Rosen, J. Kannry, and T. McGinn

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Predicting the Risk of Venous Thromboembolism in Patients Hospitalized With Heart Failure, A. Mebazaa, T. E. Spiro, H. R. Buller, L. Haskell, D. Y. Hu, R. Hull, G. Merli, S. W. Schellong, A. C. Spyropoulos, A. T. Cohen, and +2 additional authors

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A Preliminary Report on the Initiation of a Clinical Research Program in an Orthopaedic Surgery Department: Roadmaps and Tool Kits, S. L. Merwin, A. Fornari, and L. B. Lane

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MHC associations with clinical and autoantibody manifestations in European SLE, D. L. Morris, M. M. A. Fernando, K. E. Taylor, S. A. Chung, J. Nititham, M. E. Alarcon-Riquelme, L. F. Barcelloss, T. W. Behrens, P. K. Gregersen, Con Syst Lupus Erythematosus Genet, and +13 additional authors

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Factors associated with inconsistent condom use in adolescents with negative or unknown HIV status in Northwest Cameroon, L. Morris, F. Kouya, R. Kwalar, M. Pilapil, K. Saito, N. Palmer, R. Posada, P. M. Tih, T. Welty, and J. Jao

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Comment on 'effectiveness and safety of rapid clozapine titration in schizophrenia' Reply, J. Nielsen, P. Ifteni, P. Manu, J. Kane, and C. Correll

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Physician practices regarding contraindications to oral anticoagulation in atrial fibrillation: Findings from the Outcomes Registry for Better Informed Treatment of Atrial Fibrillation (ORBIT-AF) registry, E. C. O'Brien, D. N. Holmes, J. E. Ansell, L. A. Allen, E. Hylek, P. R. Kowey, B. J. Gersh, G. C. Fonarow, C. R. Koller, D. E. Singer, and +5 additional authors

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Integration of Sequence Data from a Consanguineous Family with Genetic Data from an Outbred Population Identifies PLB1 as a Candidate Rheumatoid Arthritis Risk Gene, Y. Okada, D. Diogo, J. D. Greenberg, F. Mouassess, W. A. L. Achkar, R. S. Fulton, J. C. Denny, N. Gupta, P. K. Gregersen, R. M. Plenge, and +38 additional authors

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Fine Mapping Major Histocompatibility Complex Associations in Psoriasis and Its Clinical Subtypes, Y. Okada, B. Han, L. C. Tsoi, P. E. Stuart, E. Ellinghaus, T. Tejasvi, V. Chandran, F. Pellett, P. K. Gregersen, S. Raychaudhuri, and +12 additional authors

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Genetics of rheumatoid arthritis contributes to biology and drug discovery, Y. Okada, D. Wu, G. Trynka, T. Raj, C. Terao, K. Ikari, Y. Kochi, K. Ohmura, P. K. Gregersen, R. M. Plenge, and +85 additional authors

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The relationship between the timing of a palliative care consult and utilization outcomes for ventilator-assisted intensive care unit patients, S. Pereira, A. Kozikowski, R. Pekmezaris, S. Sunday, T. Mir, M. Saad, L. Corrado, and G. Wolf-Klein

Management of Anticoagulants in the Periprocedural Period for Patients With Cancer, A. Pudusseri and A. C. Spyropoulos

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HLA-DRB1-Associated Rheumatoid Arthritis Risk at Multiple Levels in African Americans Hierarchical Classification Systems, Amino Acid Positions, and Residues, R. J. Reynolds, A. F. Ahmed, M. I. Danila, L. B. Hughes, P. K. Gregersen, S. Raychaudhuri, R. M. Plenge, S. L. Bridges, and Af Consortium Longitudinal Evaluat

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External Validation of the Risk Assessment Model of the International Medical Prevention Registry on Venous Thromboembolism (IMPROVE) for Medical Patients in a Tertiary Health System, D. Rosenberg, A. Eichorn, M. Alarcon, L. McCullagh, T. McGinn, and A. Spyropoulos

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A Role for Noncoding Variation in Schizophrenia, P. Roussos, A. C. Mitchell, G. Voloudakis, J. F. Fullard, V. M. Pothula, J. Tsang, E. A. Stahl, A. Georgakopoulos, P. K. Gregersen, P. Sklar, and +15 additional authors

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Brief motivational enhancement intervention to prevent or reduce postpartum alcohol use: a single-blinded, randomized controlled effectiveness trial, D. M. Rubio, N. L. Day, J. Conigliaro, B. H. Hanusa, C. Larkby, M. McNeil, E. Cohen, B. Jones, M. Watt-Morse, K. L. Kraemer, and +2 additional authors

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Structure and Function of Renal Macrophages and Dendritic Cells From Lupus-Prone Mice, R. Sahu, R. Bethunaickan, S. Singh, and A. Davidson

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Recognition of antigen-specific B-cell receptors from chronic lymphocytic leukemia patients by synthetic antigen surrogates, M. Sarkar, Y. Liu, J. Morimoto, H. Peng, C. Aquino, C. Rader, N. Chiorazzi, and T. Kodadek

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Outcomes of Temporary Interruption of Rivaroxaban Compared With Warfarin in Patients With Nonvalvular Atrial Fibrillation, M. W. Sherwood, J. D. Douketis, M. R. Patel, J. P. Piccini, A. S. Hellkamp, Y. Lokhnygina, A. C. Spyropoulos, G. J. Hankey, D. E. Singer, R. C. Becker, and +4 additional authors

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An analysis of pancreas transplantation outcomes based on age groupings - an update of the UNOS database, E. Siskind, C. Maloney, M. Akerman, A. Alex, S. Ashburn, M. Barlow, T. Siskind, M. Bhaskaran, N. Ali, A. Basu, E. Molmenti, and J. Ortiz

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C1q-mediated repression of human monocytes is regulated by LAIR-1, M. Son and B. Diamond

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Outcomes registry for better informed treatment of atrial fibrillation II: Rationale and design of the ORBIT-AF II registry, B. A. Steinberg, R. G. Blanco, D. Ollis, S. Kim, D. N. Holmes, P. R. Kowey, G. C. Fonarow, J. Ansell, B. Gersh, J. P. Piccini, and +6 additional authors